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Effects of curcuminoids identified in rhizomes of Curcuma longa on BACE-1 inhibitory and behavioral activity and lifespan of Alzheimer’s disease Drosophila models

Overview of attention for article published in BMC Complementary Medicine and Therapies, March 2014
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2 X users

Citations

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70 Dimensions

Readers on

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120 Mendeley
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Title
Effects of curcuminoids identified in rhizomes of Curcuma longa on BACE-1 inhibitory and behavioral activity and lifespan of Alzheimer’s disease Drosophila models
Published in
BMC Complementary Medicine and Therapies, March 2014
DOI 10.1186/1472-6882-14-88
Pubmed ID
Authors

Xue Wang, Jun-Ran Kim, Seong-Baek Lee, Young-Joon Kim, Moon Young Jung, Hyung-Wook Kwon, Young-Joon Ahn

Abstract

Alzheimer's disease (AD) is the most common type of presenile and senile dementia. The human β-amyloid precursor cleavage enzyme (BACE-1) is a key enzyme responsible for amyloid plaque production, which implicates the progress and symptoms of AD. Here we assessed the anti-BACE-1 and behavioral activities of curcuminoids from rhizomes of Curcuma longa (Zingiberaceae), diarylalkyls curcumin (CCN), demethoxycurcumin (DMCCN), and bisdemethoxycurcumin (BDMCCN) against AD Drosophila melanogaster models.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 120 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 <1%
Portugal 1 <1%
Unknown 118 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 21 18%
Student > Bachelor 21 18%
Researcher 11 9%
Student > Doctoral Student 8 7%
Other 7 6%
Other 20 17%
Unknown 32 27%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 14%
Pharmacology, Toxicology and Pharmaceutical Science 13 11%
Medicine and Dentistry 13 11%
Biochemistry, Genetics and Molecular Biology 10 8%
Neuroscience 8 7%
Other 24 20%
Unknown 35 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 May 2015.
All research outputs
#14,718,998
of 23,577,654 outputs
Outputs from BMC Complementary Medicine and Therapies
#1,710
of 3,712 outputs
Outputs of similar age
#119,870
of 222,679 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#42
of 78 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,712 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.0. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 222,679 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 78 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.