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Mendeley readers
Attention Score in Context
| Title |
Isomer-specific effects of CLA on gene expression in human adipose tissue depending on PPARγ2 P12A polymorphism: a double blind, randomized, controlled cross-over study
|
|---|---|
| Published in |
Lipids in Health and Disease, August 2009
|
| DOI | 10.1186/1476-511x-8-35 |
| Pubmed ID | |
| Authors |
J Herrmann, D Rubin, R Häsler, U Helwig, M Pfeuffer, A Auinger, C Laue, P Winkler, S Schreiber, D Bell, J Schrezenmeir |
| Abstract |
Peroxisome proliferator-activated receptor (PPAR)gamma is a key regulator in adipose tissue. The rare variant Pro12Ala of PPARgamma2 is associated with a decreased risk of insulin resistance. Being dietary PPARgamma ligands, conjugated linoleic acids (CLAs) received considerable attention because of their effects on body composition, cancer, atherosclerosis, diabetes, obesity and inflammation, although some effects were only demonstrated in animal trials and the results in human studies were not always consistent. In the present study effects of CLA supplementation on genome wide gene expression in adipose tissue biopsies from 11 Ala12Ala and 23 Pro12Pro men were investigated. Subjects underwent four intervention periods (4 wk) in a randomized double blind cross-over design receiving 4.25 g/d of either cis-9, trans-11 CLA, trans-10,cis-12 CLA, 1:1 mixture of both isomers or a reference linoleic acid oil preparation. After each intervention biopsies were taken, whole genome expression microarrays were applied, and genes of interest were verified by realtime PCR. |
Mendeley readers
The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Unknown | 76 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 18 | 23% |
| Student > Master | 11 | 14% |
| Student > Bachelor | 10 | 13% |
| Student > Ph. D. Student | 7 | 9% |
| Student > Doctoral Student | 6 | 8% |
| Other | 15 | 19% |
| Unknown | 10 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 24 | 31% |
| Medicine and Dentistry | 15 | 19% |
| Biochemistry, Genetics and Molecular Biology | 11 | 14% |
| Nursing and Health Professions | 3 | 4% |
| Chemistry | 3 | 4% |
| Other | 5 | 6% |
| Unknown | 16 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 December 2022.
All research outputs
#2,485,199
of 25,371,288 outputs
Outputs from Lipids in Health and Disease
#180
of 1,609 outputs
Outputs of similar age
#8,686
of 118,591 outputs
Outputs of similar age from Lipids in Health and Disease
#2
of 8 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,609 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.3. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 118,591 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.