Title |
Evaluation of the antibacterial potential of Petroselinum crispum and Rosmarinus officinalis against bacteria that cause urinary tract infections
|
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Published in |
Brazilian Journal of Microbiology, September 2013
|
DOI | 10.1590/s1517-83822013005000061 |
Pubmed ID | |
Authors |
Fernanda Villas Boas Petrolini, Rodrigo Lucarini, Maria Gorete Mendes de Souza, Regina Helena Pires, Wilson Roberto Cunha, Carlos Henrique Gomes Martins |
Abstract |
In this study we evaluated the antibacterial activity of the crude hydroalcoholic extracts, fractions, and compounds of two plant species, namely Rosmarinus officinalis and Petroselinum crispum, against the bacteria that cause urinary tract infection. The microdilution method was used for determination of the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The crude hydroalcoholic extract of R. officinalis displayed in vitro activity against Gram-positive bacteria, with satisfactory MBC for the clinical isolate S. saprophyticus. The fractions and the pure compound rosmarinic acid did not furnish promising results for Gram-negative bacteria, whereas fractions 2, 3, and 4 gave encouraging results for Gram-positive bacteria and acted as bactericide against S. epidermidis as well as E. faecalis (ATCC 29212) and its clinical isolate. R. officinalis led to promising results in the case of Gram-positive bacteria, resulting in a considerable interest in the development of reliable alternatives for the treatment of urinary infections. |
X Demographics
Geographical breakdown
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United States | 2 | 50% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
Geographical breakdown
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Lithuania | 1 | 1% |
Germany | 1 | 1% |
Honduras | 1 | 1% |
Unknown | 72 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 13 | 17% |
Student > Doctoral Student | 10 | 13% |
Student > Bachelor | 10 | 13% |
Researcher | 9 | 12% |
Student > Ph. D. Student | 9 | 12% |
Other | 10 | 13% |
Unknown | 14 | 19% |
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Pharmacology, Toxicology and Pharmaceutical Science | 8 | 11% |
Biochemistry, Genetics and Molecular Biology | 6 | 8% |
Chemistry | 5 | 7% |
Other | 12 | 16% |
Unknown | 18 | 24% |