Title |
Aberrant Mucin5B expression in lung adenocarcinomas detected by iTRAQ labeling quantitative proteomics and immunohistochemistry
|
---|---|
Published in |
Clinical Proteomics, November 2013
|
DOI | 10.1186/1559-0275-10-15 |
Pubmed ID | |
Authors |
Yan Li, Xiangchun Wang, MingHui Ao, Edward Gabrielson, Frederic Askin, Hui Zhang, Qing Kay Li |
Abstract |
Lung cancer is the number one cause of cancer-related deaths in the United States and worldwide. The complex protein changes and/or signature of protein expression in lung cancer, particularly in non-small cell lung cancer (NSCLC) has not been well defined. Although several studies have investigated the protein profile in lung cancers, the knowledge is far from complete. Among early studies, mucin5B (MUC5B) has been suggested to play an important role in the tumor progression. MUC5B is the major gel-forming mucin in the airway. In this study, we investigated the overall protein profile and MUC5B expression in lung adenocarcinomas, the most common type of NSCLCs. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 34 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 8 | 24% |
Researcher | 8 | 24% |
Student > Postgraduate | 4 | 12% |
Student > Master | 4 | 12% |
Student > Doctoral Student | 2 | 6% |
Other | 4 | 12% |
Unknown | 4 | 12% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 9 | 26% |
Medicine and Dentistry | 8 | 24% |
Agricultural and Biological Sciences | 5 | 15% |
Chemistry | 3 | 9% |
Computer Science | 1 | 3% |
Other | 2 | 6% |
Unknown | 6 | 18% |