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A salt-bridge structure in solution revealed by 2D-IR spectroscopy

Overview of attention for article published in Journal of the Chemical Society, Faraday Transactions, January 2014
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3 X users

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Title
A salt-bridge structure in solution revealed by 2D-IR spectroscopy
Published in
Journal of the Chemical Society, Faraday Transactions, January 2014
DOI 10.1039/c4cp00233d
Pubmed ID
Authors

Adriana Huerta-Viga, Sérgio R. Domingos, Saeed Amirjalayer, Sander Woutersen

Abstract

Salt bridges are important interactions for the stability of protein conformations, but up to now it has been difficult to determine salt-bridge geometries in solution. Here we characterize the spatial structure of a salt bridge between guanidinium (Gdm(+)) and acetate (Ac(-)) using two-dimensional vibrational (2D-IR) spectroscopy. We find that as a result of salt bridge formation there is a significant change in the infrared response of Gdm(+) and Ac(-), and cross peaks between them appear in the 2D-IR spectrum. From the 2D-IR spectrum we determine the relative orientation of the transition-dipole moments of the vibrational modes of Gdm(+) and Ac(-), as well as the coupling between them.

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 50%
Researcher 3 19%
Professor 1 6%
Other 1 6%
Student > Master 1 6%
Other 1 6%
Unknown 1 6%
Readers by discipline Count As %
Chemistry 10 63%
Agricultural and Biological Sciences 1 6%
Physics and Astronomy 1 6%
Engineering 1 6%
Unknown 3 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 April 2014.
All research outputs
#15,775,925
of 25,756,911 outputs
Outputs from Journal of the Chemical Society, Faraday Transactions
#6,098
of 17,201 outputs
Outputs of similar age
#183,037
of 321,307 outputs
Outputs of similar age from Journal of the Chemical Society, Faraday Transactions
#246
of 524 outputs
Altmetric has tracked 25,756,911 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 17,201 research outputs from this source. They receive a mean Attention Score of 2.5. This one has gotten more attention than average, scoring higher than 63% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 321,307 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 524 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.