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MicroRNA-155 as a proinflammatory regulator via SHIP-1 down-regulation in acute gouty arthritis

Overview of attention for article published in Arthritis Research & Therapy, April 2014
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Title
MicroRNA-155 as a proinflammatory regulator via SHIP-1 down-regulation in acute gouty arthritis
Published in
Arthritis Research & Therapy, April 2014
DOI 10.1186/ar4531
Pubmed ID
Authors

Hye Mi Jin, Tae-Jong Kim, Jung-Ho Choi, Moon-Ju Kim, Young-Nan Cho, Kwang-Il Nam, Seung-Jung Kee, Jang Bae Moon, Seok-Yong Choi, Dong-Jin Park, Shin-Seok Lee, Yong-Wook Park

Abstract

Gout is characterized by episodes of intense joint inflammation in response to intra-articular monosodium urate monohydrate (MSU) crystals. miR-155 is crucial for the proinflammatory activation of human myeloid cells and antigen-driven inflammatory arthritis. The functional role of miR-155 in acute gouty arthritis has not been defined. Therefore, the aim of this study was to examine the role of miR-155 in pathogenesis of acute gouty arthritis.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Australia 1 2%
Brazil 1 2%
Unknown 42 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 20%
Researcher 6 13%
Student > Doctoral Student 6 13%
Other 4 9%
Student > Master 3 7%
Other 8 18%
Unknown 9 20%
Readers by discipline Count As %
Medicine and Dentistry 14 31%
Agricultural and Biological Sciences 6 13%
Biochemistry, Genetics and Molecular Biology 5 11%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Immunology and Microbiology 2 4%
Other 6 13%
Unknown 10 22%