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Omalizumab may decrease IgE synthesis by targeting membrane IgE+ human B cells

Overview of attention for article published in Clinical and Translational Allergy, September 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (59th percentile)

Mentioned by

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1 patent
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1 research highlight platform

Citations

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55 Dimensions

Readers on

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76 Mendeley
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Title
Omalizumab may decrease IgE synthesis by targeting membrane IgE+ human B cells
Published in
Clinical and Translational Allergy, September 2013
DOI 10.1186/2045-7022-3-29
Pubmed ID
Authors

Marcia A Chan, Nicole M Gigliotti, Abby L Dotson, Lanny J Rosenwasser

Abstract

Omalizumab, is a humanized anti-IgE monoclonal antibody used to treat allergic asthma. Decreased serum IgE levels, lower eosinophil and B cell counts have been noted as a result of treatment. In vitro studies and animal models support the hypothesis that omalizumab inhibits IgE synthesis by B cells and causes elimination of IgE-expressing cells either by induction of apoptosis or induction of anergy or tolerance.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 1%
Unknown 75 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 17%
Student > Bachelor 13 17%
Student > Ph. D. Student 9 12%
Student > Doctoral Student 5 7%
Professor 3 4%
Other 13 17%
Unknown 20 26%
Readers by discipline Count As %
Medicine and Dentistry 19 25%
Agricultural and Biological Sciences 14 18%
Biochemistry, Genetics and Molecular Biology 10 13%
Immunology and Microbiology 5 7%
Pharmacology, Toxicology and Pharmaceutical Science 4 5%
Other 2 3%
Unknown 22 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 May 2019.
All research outputs
#7,356,343
of 25,374,917 outputs
Outputs from Clinical and Translational Allergy
#399
of 756 outputs
Outputs of similar age
#59,842
of 210,221 outputs
Outputs of similar age from Clinical and Translational Allergy
#8
of 22 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 756 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.7. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,221 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.