Title |
DNA methylation study of fetus genome through a genome-wide analysis
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Published in |
BMC Medical Genomics, April 2014
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DOI | 10.1186/1755-8794-7-18 |
Pubmed ID | |
Authors |
Hong-Dan Wang, Qiao-Fang Hou, Qian-Nan Guo, Tao Li, Dong Wu, Xian-Ping Zhang, Yan Chu, Miao He, Hai Xiao, Liang-Jie Guo, Ke Yang, Shi-Xiu Liao, Bo-Feng Zhu |
Abstract |
DNA methylation is a crucial epigenetic modification of the genome which is involved in embryonic development, transcription, chromatin structure, X chromosome inactivation, genomic imprinting and chromosome stability. Consistent with these important roles, DNA methylation has been demonstrated to be required for vertebrate early embryogenesis and essential for regulating temporal and spatial expression of genes controlling cell fate and differentiation. Further studies have shown that abnormal DNA methylation is associated with human diseases including the embryonic development diseases. We attempt to study the DNA methylation status of CpG islands in fetus related to fetus growth and development. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Spain | 1 | 3% |
Italy | 1 | 3% |
Unknown | 31 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 9 | 27% |
Student > Ph. D. Student | 7 | 21% |
Professor > Associate Professor | 4 | 12% |
Student > Master | 3 | 9% |
Student > Doctoral Student | 2 | 6% |
Other | 5 | 15% |
Unknown | 3 | 9% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 8 | 24% |
Medicine and Dentistry | 7 | 21% |
Biochemistry, Genetics and Molecular Biology | 5 | 15% |
Nursing and Health Professions | 2 | 6% |
Neuroscience | 2 | 6% |
Other | 6 | 18% |
Unknown | 3 | 9% |