↓ Skip to main content

Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models

Overview of attention for article published in Stem Cell Research & Therapy, April 2014
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

news
1 news outlet
blogs
1 blog

Citations

dimensions_citation
106 Dimensions

Readers on

mendeley
119 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models
Published in
Stem Cell Research & Therapy, April 2014
DOI 10.1186/scrt440
Pubmed ID
Authors

Mathew Blurton-Jones, Brian Spencer, Sara Michael, Nicholas A Castello, Andranik A Agazaryan, Joy L Davis, Franz-Josef Müller, Jeanne F Loring, Eliezer Masliah, Frank M LaFerla

Abstract

Short-term neural stem cell (NSC) transplantation improves cognition in Alzheimer's disease (AD) transgenic mice by enhancing endogenous synaptic connectivity. However, this approach has no effect on the underlying beta-amyloid (Aβ) and neurofibrillary tangle pathology. Long term efficacy of cell based approaches may therefore require combinatorial approaches.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Spain 1 <1%
Portugal 1 <1%
Unknown 116 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 29 24%
Student > Ph. D. Student 21 18%
Student > Master 15 13%
Researcher 10 8%
Professor > Associate Professor 6 5%
Other 15 13%
Unknown 23 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 29 24%
Biochemistry, Genetics and Molecular Biology 20 17%
Neuroscience 18 15%
Medicine and Dentistry 10 8%
Engineering 6 5%
Other 10 8%
Unknown 26 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 September 2014.
All research outputs
#2,424,173
of 22,753,345 outputs
Outputs from Stem Cell Research & Therapy
#173
of 2,415 outputs
Outputs of similar age
#23,542
of 203,744 outputs
Outputs of similar age from Stem Cell Research & Therapy
#2
of 29 outputs
Altmetric has tracked 22,753,345 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,415 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 203,744 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.