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Mendeley readers
| Title |
Amorphous silica nanoparticles size-dependently aggravate atopic dermatitis-like skin lesions following an intradermal injection
|
|---|---|
| Published in |
Particle and Fibre Toxicology, February 2012
|
| DOI | 10.1186/1743-8977-9-3 |
| Pubmed ID | |
| Authors |
Toshiro Hirai, Tomoaki Yoshikawa, Hiromi Nabeshi, Tokuyuki Yoshida, Saeko Tochigi, Ko-ichi Ichihashi, Miyuki Uji, Takanori Akase, Kazuya Nagano, Yasuhiro Abe, Haruhiko Kamada, Norio Itoh, Shin-ichi Tsunoda, Yasuo Yoshioka, Yasuo Tsutsumi |
| Abstract |
Due to the rising use of nanomaterials (NMs), there is concern that NMs induce undesirable biological effects because of their unique physicochemical properties. Recently, we reported that amorphous silica nanoparticles (nSPs), which are one of the most widely used NMs, can penetrate the skin barrier and induce various biological effects, including an immune-modulating effect. Thus, it should be clarified whether nSPs can be a risk factor for the aggravation of skin immune diseases. Thus, in this study, we investigated the relationship between the size of SPs and adjuvant activity using a model for atopic dermatitis. |
Mendeley readers
The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Unknown | 50 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 10 | 20% |
| Student > Master | 8 | 16% |
| Student > Ph. D. Student | 6 | 12% |
| Professor > Associate Professor | 3 | 6% |
| Student > Doctoral Student | 2 | 4% |
| Other | 6 | 12% |
| Unknown | 16 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 6 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 12% |
| Agricultural and Biological Sciences | 6 | 12% |
| Medicine and Dentistry | 5 | 10% |
| Immunology and Microbiology | 4 | 8% |
| Other | 7 | 14% |
| Unknown | 17 | 33% |