↓ Skip to main content

Reduced immune cell infiltration and increased pro-inflammatory mediators in the brain of Type 2 diabetic mouse model infected with West Nile virus

Overview of attention for article published in Journal of Neuroinflammation, April 2014
Altmetric Badge

About this Attention Score

  • Average Attention Score compared to outputs of the same age
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
1 X user
f1000
1 research highlight platform

Citations

dimensions_citation
61 Dimensions

Readers on

mendeley
60 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Reduced immune cell infiltration and increased pro-inflammatory mediators in the brain of Type 2 diabetic mouse model infected with West Nile virus
Published in
Journal of Neuroinflammation, April 2014
DOI 10.1186/1742-2094-11-80
Pubmed ID
Authors

Mukesh Kumar, Kelsey Roe, Pratibha V Nerurkar, Beverly Orillo, Karen S Thompson, Saguna Verma, Vivek R Nerurkar

Abstract

Diabetes is a significant risk factor for developing West Nile virus (WNV)-associated encephalitis (WNVE) in humans, the leading cause of arboviral encephalitis in the United States. Using a diabetic mouse model (db/db), we recently demonstrated that diabetes enhanced WNV replication and the susceptibility of mice to WNVE. Herein, we have examined immunological events in the brain of wild type (WT) and db/db mice after WNV infection. We hypothesized that WNV-induced migration of protective leukocytes into the brain is attenuated in the presence of diabetes, leading to a high viral load in the brain and severe disease in diabetic mice.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 60 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 13%
Researcher 7 12%
Student > Ph. D. Student 5 8%
Other 4 7%
Unspecified 4 7%
Other 10 17%
Unknown 22 37%
Readers by discipline Count As %
Medicine and Dentistry 10 17%
Biochemistry, Genetics and Molecular Biology 7 12%
Immunology and Microbiology 5 8%
Unspecified 4 7%
Agricultural and Biological Sciences 3 5%
Other 8 13%
Unknown 23 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 May 2014.
All research outputs
#14,195,272
of 22,754,104 outputs
Outputs from Journal of Neuroinflammation
#1,558
of 2,618 outputs
Outputs of similar age
#120,316
of 226,772 outputs
Outputs of similar age from Journal of Neuroinflammation
#11
of 25 outputs
Altmetric has tracked 22,754,104 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,618 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,772 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.