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Relationship of Helicobacter pylori seroprevalence with the occurrence and severity of psoriasis

Overview of attention for article published in Anais Brasileiros de Dermatologia, February 2017
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Relationship of Helicobacter pylori seroprevalence with the occurrence and severity of psoriasis
Published in
Anais Brasileiros de Dermatologia, February 2017
DOI 10.1590/abd1806-4841.20174880
Pubmed ID

Priscila Miranda Diogo Mesquita, Augusto Diogo Filho, Miguel Tanus Jorge, Alceu Luiz Camargo Villela Berbert, Sônia Antunes de Oliveira Mantese, José Joaquim Rodrigues


Psoriasis is a chronic inflammatory disease that affects the skin and joints and has a multifactorial etiology. Recently, it has been suggested that Helicobacter pylori infection may contribute as a trigger for the development of the disease. To determine the prevalence of H. pylori seropositivity in patients with psoriasis and to evaluate the relation between disease severity and H. pylori infection. H. pylori infection was assessed in psoriatic patients and controls by using H. pylori IgG quantitative enzyme immunoassay (ELISA test). The patients were classified according to the severity of the disease (PASI score). One hundred and twenty six patients with psoriasis (73 females and 53 males); mean age 50.48 years; 65 patients (51.59%) had severe psoriasis, 40 (31.75%) moderate psoriasis and 21 (16.67%) mild psoriasis. Twenty one healthy volunteers included as a control group, mean age of 41.05 years, 13 females and 8 males. One hundred and eleven patients with psoriasis tested serologically, 80 (72.07%) were seropositive compared with 7 positive volunteers (33.33%; P=0.002). Forty-nine (75.38%) patients with severe psoriasis were positive, 25 (62.50%) with moderate psoriasis were positive and 6 (28.57%) with mild psoriasis were positive (P=0.045). Study limitations: none. H. pylori infection influences the development of psoriasis and severity of the disease.

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 30%
Student > Postgraduate 3 15%
Student > Ph. D. Student 3 15%
Student > Doctoral Student 2 10%
Researcher 2 10%
Other 2 10%
Unknown 2 10%
Readers by discipline Count As %
Medicine and Dentistry 6 30%
Psychology 3 15%
Nursing and Health Professions 2 10%
Biochemistry, Genetics and Molecular Biology 2 10%
Immunology and Microbiology 2 10%
Other 3 15%
Unknown 2 10%