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Accelerating the scoring module of mass spectrometry-based peptide identification using GPUs

Overview of attention for article published in BMC Bioinformatics, April 2014
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3 X users

Citations

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25 Mendeley
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Title
Accelerating the scoring module of mass spectrometry-based peptide identification using GPUs
Published in
BMC Bioinformatics, April 2014
DOI 10.1186/1471-2105-15-121
Pubmed ID
Authors

You Li, Hao Chi, Leihao Xia, Xiaowen Chu

Abstract

Tandem mass spectrometry-based database searching is currently the main method for protein identification in shotgun proteomics. The explosive growth of protein and peptide databases, which is a result of genome translations, enzymatic digestions, and post-translational modifications (PTMs), is making computational efficiency in database searching a serious challenge. Profile analysis shows that most search engines spend 50%-90% of their total time on the scoring module, and that the spectrum dot product (SDP) based scoring module is the most widely used. As a general purpose and high performance parallel hardware, graphics processing units (GPUs) are promising platforms for speeding up database searches in the protein identification process.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 4%
Belgium 1 4%
Unknown 23 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 24%
Researcher 5 20%
Student > Bachelor 4 16%
Professor > Associate Professor 3 12%
Student > Master 3 12%
Other 4 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 36%
Computer Science 8 32%
Biochemistry, Genetics and Molecular Biology 3 12%
Engineering 3 12%
Chemistry 1 4%
Other 1 4%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 July 2015.
All research outputs
#15,867,545
of 23,577,761 outputs
Outputs from BMC Bioinformatics
#5,494
of 7,418 outputs
Outputs of similar age
#136,408
of 229,303 outputs
Outputs of similar age from BMC Bioinformatics
#86
of 137 outputs
Altmetric has tracked 23,577,761 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,418 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 229,303 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 137 others from the same source and published within six weeks on either side of this one. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.