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The Association between Regular Cannabis Exposure and Alterations of Human Brain Morphology: An Updated Review of the Literature.

Overview of attention for article published in Current Pharmaceutical Design, June 2013
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#26 of 1,630)
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

news
3 news outlets
policy
2 policy sources
twitter
1 tweeter

Citations

dimensions_citation
58 Dimensions

Readers on

mendeley
79 Mendeley
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Title
The Association between Regular Cannabis Exposure and Alterations of Human Brain Morphology: An Updated Review of the Literature.
Published in
Current Pharmaceutical Design, June 2013
DOI 10.2174/13816128113199990435
Pubmed ID
Authors

Lorenzetti V, Solowij N, Fornito A, Lubman D, Yucel M, Lorenzetti, Valentina, Solowij, Nadia, Fornito, Alex, Lubman, Dan Ian, Yucel, Murat, Valentina Lorenzetti, Nadia Solowij, Alex Fornito, Dan Lubman, Murat Yucel

Abstract

Cannabis is the most widely used illicit drug worldwide, though it is unclear whether its regular use is associated with persistent alterations in brain morphology. This review examines evidence from human structural neuroimaging investigations of regular cannabis users and focuses on achieving three main objectives. These include examining whether the literature to date provides evidence that alteration of brain morphology in regular cannabis users: i) is apparent, compared to non-cannabis using controls; ii) is associated with patterns of cannabis use; and with iii) measures of psychopathology and neurocognitive performance. The published findings indicate that regular cannabis use is associated with alterations in medial temporal, frontal and cerebellar brain regions. Greater brain morphological alterations were evident among samples that used at higher doses for longer periods. However, the evidence for an association between brain morphology and cannabis use parameters was mixed. Further, there is poor evidence for an association between measures of brain morphology and of psychopathology symptoms/neurocognitive performance. Overall, numerous methodological issues characterize the literature to date. These include investigation of small sample sizes, heterogeneity across studies in sample characteristics (e.g., sex, comorbidity) and in employed imaging techniques, as well as the examination of only a limited number of brain regions. These factors make it difficult to draw firm conclusions from the existing findings. Nevertheless, this review supports the notion that regular cannabis use is associated with alterations of brain morphology, and highlights the need to consider particular methodological issues when planning future cannabis research.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Spain 1 1%
Germany 1 1%
Unknown 76 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 20 25%
Researcher 10 13%
Student > Bachelor 10 13%
Student > Doctoral Student 8 10%
Student > Postgraduate 8 10%
Other 20 25%
Unknown 3 4%
Readers by discipline Count As %
Psychology 25 32%
Medicine and Dentistry 15 19%
Neuroscience 14 18%
Agricultural and Biological Sciences 3 4%
Social Sciences 3 4%
Other 11 14%
Unknown 8 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 34. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 February 2017.
All research outputs
#310,940
of 9,031,633 outputs
Outputs from Current Pharmaceutical Design
#26
of 1,630 outputs
Outputs of similar age
#7,542
of 180,020 outputs
Outputs of similar age from Current Pharmaceutical Design
#1
of 12 outputs
Altmetric has tracked 9,031,633 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,630 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 180,020 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.