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Inhibition of the JAK2/STAT3 pathway in ovarian cancer results in the loss of cancer stem cell-like characteristics and a reduced tumor burden

Overview of attention for article published in BMC Cancer, May 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

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5 X users
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1 patent

Citations

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104 Dimensions

Readers on

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84 Mendeley
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Title
Inhibition of the JAK2/STAT3 pathway in ovarian cancer results in the loss of cancer stem cell-like characteristics and a reduced tumor burden
Published in
BMC Cancer, May 2014
DOI 10.1186/1471-2407-14-317
Pubmed ID
Authors

Khalid Abubaker, Rodney B Luwor, Hongjian Zhu, Orla McNally, Michael A Quinn, Christopher J Burns, Erik W Thompson, Jock K Findlay, Nuzhat Ahmed

Abstract

Current treatment of ovarian cancer patients with chemotherapy leaves behind a residual tumor which results in recurrent ovarian cancer within a short time frame. We have previously demonstrated that a single short-term treatment of ovarian cancer cells with chemotherapy in vitro resulted in a cancer stem cell (CSC)-like enriched residual population which generated significantly greater tumor burden compared to the tumor burden generated by control untreated cells. In this report we looked at the mechanisms of the enrichment of CSC-like residual cells in response to paclitaxel treatment.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Unknown 82 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 19 23%
Student > Ph. D. Student 15 18%
Student > Bachelor 14 17%
Student > Master 11 13%
Student > Postgraduate 4 5%
Other 7 8%
Unknown 14 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 22 26%
Biochemistry, Genetics and Molecular Biology 20 24%
Medicine and Dentistry 10 12%
Immunology and Microbiology 3 4%
Psychology 2 2%
Other 8 10%
Unknown 19 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 April 2021.
All research outputs
#5,405,999
of 22,755,127 outputs
Outputs from BMC Cancer
#1,314
of 8,275 outputs
Outputs of similar age
#50,716
of 227,400 outputs
Outputs of similar age from BMC Cancer
#18
of 134 outputs
Altmetric has tracked 22,755,127 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,275 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,400 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 134 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.