Title |
Reduced expression of ezrin in urothelial bladder cancer signifies more advanced tumours and an impaired survival: validatory study of two independent patient cohorts
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Published in |
BMC Urology, May 2014
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DOI | 10.1186/1471-2490-14-36 |
Pubmed ID | |
Authors |
Gustav Andersson, Christoffer Wennersten, Alexander Gaber, Karolina Boman, Björn Nodin, Mathias Uhlén, Ulrika Segersten, Per-Uno Malmström, Karin Jirström |
Abstract |
Reduced membranous expression of the cytoskeleton-associated protein ezrin has previously been demonstrated to correlate with tumour progression and poor prognosis in patients with T1G3 urothelial cell carcinoma of the bladder treated with non-maintenance Bacillus Calmette-Guérin (n = 92), and the associations with adverse clinicopathological factors have been validated in another, unselected, cohort (n = 104). In the present study, we examined the prognostic significance of ezrin expression in urothelial bladder cancer in a total number of 442 tumours from two independent patient cohorts. |
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United Kingdom | 1 | 100% |
Demographic breakdown
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Mendeley readers
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Demographic breakdown
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Student > Ph. D. Student | 2 | 12% |
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Economics, Econometrics and Finance | 1 | 6% |
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