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X Demographics
Mendeley readers
Attention Score in Context
| Title |
4sUDRB-seq: measuring genomewide transcriptional elongation rates and initiation frequencies within cells
|
|---|---|
| Published in |
Genome Biology, May 2014
|
| DOI | 10.1186/gb-2014-15-5-r69 |
| Pubmed ID | |
| Authors |
Gilad Fuchs, Yoav Voichek, Sima Benjamin, Shlomit Gilad, Ido Amit, Moshe Oren |
| Abstract |
Although transcriptional elongation by RNA polymerase II is coupled with many RNA-related processes, genomewide elongation rates remain unknown. We describe a method, called 4sUDRB-seq, based on reversible inhibition of transcription elongation coupled with tagging newly transcribed RNA with 4-thiouridine and high throughput sequencing to measure simultaneously with high confidence genome-wide transcription elongation rates in cells. We find that most genes are transcribed at about 3.5 Kb/min, with elongation rates varying between 2 Kb/min and 6 Kb/min. 4sUDRB-seq can facilitate genomewide exploration of the involvement of specific elongation factors in transcription and the contribution of deregulated transcription elongation to various pathologies. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 30% |
| United States | 2 | 20% |
| France | 1 | 10% |
| Australia | 1 | 10% |
| Unknown | 3 | 30% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 60% |
| Scientists | 3 | 30% |
| Science communicators (journalists, bloggers, editors) | 1 | 10% |
Mendeley readers
The data shown below were compiled from readership statistics for 199 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 1% |
| Korea, Republic of | 1 | <1% |
| Austria | 1 | <1% |
| Sweden | 1 | <1% |
| Germany | 1 | <1% |
| Israel | 1 | <1% |
| Japan | 1 | <1% |
| United States | 1 | <1% |
| Luxembourg | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 189 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 57 | 29% |
| Researcher | 44 | 22% |
| Student > Master | 26 | 13% |
| Student > Bachelor | 15 | 8% |
| Professor | 9 | 5% |
| Other | 24 | 12% |
| Unknown | 24 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 85 | 43% |
| Agricultural and Biological Sciences | 70 | 35% |
| Medicine and Dentistry | 7 | 4% |
| Physics and Astronomy | 2 | 1% |
| Computer Science | 2 | 1% |
| Other | 7 | 4% |
| Unknown | 26 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 27. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 January 2021.
All research outputs
#1,431,487
of 25,374,647 outputs
Outputs from Genome Biology
#1,138
of 4,467 outputs
Outputs of similar age
#13,907
of 241,873 outputs
Outputs of similar age from Genome Biology
#7
of 38 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 241,873 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.