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Dietary antioxidants: immunity and host defense.

Overview of attention for article published in Current Topics in Medicinal Chemistry, April 2011
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#2 of 1,139)
  • High Attention Score compared to outputs of the same age (97th percentile)

Mentioned by

5 news outlets
1 blog
1 tweeter
1 Wikipedia page
1 video uploader


72 Dimensions

Readers on

74 Mendeley
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Dietary antioxidants: immunity and host defense.
Published in
Current Topics in Medicinal Chemistry, April 2011
DOI 10.2174/156802611796235107
Pubmed ID

Puertollano MA, Puertollano E, de Cienfuegos GÁ, de Pablo MA, María A Puertollano, Elena Puertollano, Gerardo Álvarez de Cienfuegos, Manuel A de Pablo, A. Puertollano, Maria, Puertollano, Elena, Alvarez de Cienfuegos, Gerardo, A. de Pablo, Manuel, Maria A. Puertollano, Gerardo Alvarez de Cienfuegos, Manuel A. de Pablo


Natural antioxidants may be defined as molecules that prevent cell damage against free radicals and are critical for maintaining optimum health in both animals and humans. In all living systems, cells require adequate levels of antioxidant defenses in order to avoid the harmful effect of an excessive production of reactive oxygen species (ROS) and to prevent damage to the immune cells. During the inflammatory processes, the activation of phagocytes and/or the action of bacterial products with specific receptors are capable of promoting the assembly of the multicomponent flavoprotein NADPH oxidase, which catalyzes the production of high amounts of the superoxide anion radical (O(2)(-)). Under these particular circumstances, neutrophils and macrophages are recognized to produce superoxide free radicals and H(2)O(2), which are essential for defence against phagocytized or invading microbes. In this state, antioxidants are absolutely necessary to regulate the reactions that release free radicals. Antioxidant nutrients commonly included in the diet such as vitamin E, vitamin C, β-carotene, selenium, copper, iron and zinc improve different immune function exhibiting an important protective role in infections caused by bacteria, viruses or parasites. As a result, dietary antioxidants have been related to modulate the host susceptibility or resistance to infectious pathogens. Overall, numerous studies have suggested that the development of tolerance, and control of inflammation are strongly correlated with specific immune mechanisms that may be altered by an inadequate supply of either macronutrients or micronutrients. Therefore, the present paper will review the effects of dietary antioxidants on immune cell function and the impact on protection against infectious microorganisms.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Bulgaria 1 1%
France 1 1%
United States 1 1%
Unknown 71 96%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 17 23%
Student > Ph. D. Student 11 15%
Researcher 11 15%
Student > Master 9 12%
Unspecified 8 11%
Other 18 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 23%
Medicine and Dentistry 12 16%
Biochemistry, Genetics and Molecular Biology 11 15%
Unspecified 10 14%
Chemistry 5 7%
Other 19 26%

Attention Score in Context

This research output has an Altmetric Attention Score of 55. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 February 2019.
All research outputs
of 12,712,279 outputs
Outputs from Current Topics in Medicinal Chemistry
of 1,139 outputs
Outputs of similar age
of 188,465 outputs
Outputs of similar age from Current Topics in Medicinal Chemistry
of 4 outputs
Altmetric has tracked 12,712,279 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,139 research outputs from this source. They receive a mean Attention Score of 3.5. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 188,465 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them