Title |
Biomarkers of early sepsis may be correlated with outcome
|
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Published in |
Journal of Translational Medicine, May 2014
|
DOI | 10.1186/1479-5876-12-146 |
Pubmed ID | |
Authors |
Tsai-Hsia Hong, Chin-Hao Chang, Wen-Je Ko, Ching-Feng Lin, Heng-Hsiu Liu, Lu-Ping Chow, Chun-Ta Huang, Sun-Liang Yu, Yih-Sharng Chen |
Abstract |
Sepsis causes high mortality, and the mortality due to secondary infections is even higher. No studies to date have investigated the time from the primary infection to death due to a secondary infection; similarly, the factors that are significantly different in sepsis survivors relative to non-survivors or in severe sepsis patients who suffered a late death relative to those who recover have not been explored. We hypothesized that patients who survive sepsis have a weaker pro-inflammatory response than those who do not and that the mid-term survivors (which acquire secondary infections) would have a pronounced anti-inflammatory response (making them susceptible to infection); this hypothesis was verified in this study. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Indonesia | 1 | 2% |
Unknown | 43 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 8 | 18% |
Student > Master | 8 | 18% |
Student > Postgraduate | 5 | 11% |
Student > Doctoral Student | 3 | 7% |
Student > Ph. D. Student | 3 | 7% |
Other | 8 | 18% |
Unknown | 9 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 20 | 45% |
Agricultural and Biological Sciences | 4 | 9% |
Biochemistry, Genetics and Molecular Biology | 3 | 7% |
Nursing and Health Professions | 3 | 7% |
Immunology and Microbiology | 2 | 5% |
Other | 3 | 7% |
Unknown | 9 | 20% |