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Neuroinflammation and M2 microglia: the good, the bad, and the inflamed

Overview of attention for article published in Journal of Neuroinflammation, January 2014
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#25 of 1,830)
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

news
4 news outlets
blogs
1 blog
twitter
6 tweeters
patent
1 patent
facebook
2 Facebook pages

Citations

dimensions_citation
607 Dimensions

Readers on

mendeley
1001 Mendeley
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Title
Neuroinflammation and M2 microglia: the good, the bad, and the inflamed
Published in
Journal of Neuroinflammation, January 2014
DOI 10.1186/1742-2094-11-98
Pubmed ID
Authors

Jonathan D Cherry, John A Olschowka, M O’Banion

Abstract

The concept of multiple macrophage activation states is not new. However, extending this idea to resident tissue macrophages, like microglia, has gained increased interest in recent years. Unfortunately, the research on peripheral macrophage polarization does not necessarily translate accurately to their central nervous system (CNS) counterparts. Even though pro- and anti-inflammatory cytokines can polarize microglia to distinct activation states, the specific functions of these states is still an area of intense debate. This review examines the multiple possible activation states microglia can be polarized to. This is followed by a detailed description of microglial polarization and the functional relevance of this process in both acute and chronic CNS disease models described in the literature. Particular attention is given to utilizing M2 microglial polarization as a potential therapeutic option in treating diseases.

Twitter Demographics

The data shown below were collected from the profiles of 6 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 1,001 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 8 <1%
United Kingdom 3 <1%
Spain 2 <1%
France 2 <1%
South Africa 1 <1%
Italy 1 <1%
Indonesia 1 <1%
Canada 1 <1%
Mexico 1 <1%
Other 3 <1%
Unknown 978 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 240 24%
Student > Bachelor 182 18%
Student > Master 169 17%
Researcher 140 14%
Student > Doctoral Student 69 7%
Other 117 12%
Unknown 84 8%
Readers by discipline Count As %
Neuroscience 260 26%
Agricultural and Biological Sciences 241 24%
Biochemistry, Genetics and Molecular Biology 128 13%
Medicine and Dentistry 123 12%
Pharmacology, Toxicology and Pharmaceutical Science 35 3%
Other 95 9%
Unknown 119 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 46. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 May 2020.
All research outputs
#453,514
of 15,127,930 outputs
Outputs from Journal of Neuroinflammation
#25
of 1,830 outputs
Outputs of similar age
#6,703
of 190,958 outputs
Outputs of similar age from Journal of Neuroinflammation
#1
of 16 outputs
Altmetric has tracked 15,127,930 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,830 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 190,958 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.