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Methylation analysis and diagnostics of Beckwith-Wiedemann syndrome in 1,000 subjects

Overview of attention for article published in Clinical Epigenetics, January 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (70th percentile)

Mentioned by

twitter
6 tweeters

Citations

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74 Dimensions

Readers on

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45 Mendeley
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Title
Methylation analysis and diagnostics of Beckwith-Wiedemann syndrome in 1,000 subjects
Published in
Clinical Epigenetics, January 2014
DOI 10.1186/1868-7083-6-11
Pubmed ID
Authors

Abdulla Ibrahim, Gail Kirby, Carol Hardy, Renuka P Dias, Louise Tee, Derek Lim, Jonathan Berg, Fiona MacDonald, Peter Nightingale, Eamonn R Maher

Abstract

Beckwith-Wiedemann syndrome (BWS), a congenital overgrowth disorder with variable expressivity and a predisposition to tumorigenesis, results from disordered expression and/or function of imprinted genes at chromosome 11p15.5. There are no generally agreed clinical diagnostic criteria, with molecular studies commonly performed to confirm diagnosis. In particular, methylation status analysis at two 11p15.5 imprinting control centres (IC1 and IC2) detects up to 80% of BWS cases (though low-level mosaicism may not be detected). In order to evaluate the relationship between the clinical presentation of suspected BWS and IC1/2 methylation abnormalities we reviewed the results of >1,000 referrals for molecular diagnostic testing.

Twitter Demographics

The data shown below were collected from the profiles of 6 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 45 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 20%
Student > Ph. D. Student 6 13%
Student > Master 6 13%
Student > Bachelor 6 13%
Other 4 9%
Other 8 18%
Unknown 6 13%
Readers by discipline Count As %
Medicine and Dentistry 16 36%
Biochemistry, Genetics and Molecular Biology 13 29%
Agricultural and Biological Sciences 5 11%
Computer Science 1 2%
Psychology 1 2%
Other 1 2%
Unknown 8 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 July 2014.
All research outputs
#4,556,490
of 15,248,235 outputs
Outputs from Clinical Epigenetics
#334
of 790 outputs
Outputs of similar age
#54,847
of 191,162 outputs
Outputs of similar age from Clinical Epigenetics
#1
of 2 outputs
Altmetric has tracked 15,248,235 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 790 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 191,162 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them