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Characterisation of marsupial PHLDA2 reveals eutherian specific acquisition of imprinting

Overview of attention for article published in BMC Ecology and Evolution, August 2011
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Title
Characterisation of marsupial PHLDA2 reveals eutherian specific acquisition of imprinting
Published in
BMC Ecology and Evolution, August 2011
DOI 10.1186/1471-2148-11-244
Pubmed ID
Authors

Shunsuke Suzuki, Geoffrey Shaw, Tomoko Kaneko-Ishino, Fumitoshi Ishino, Marilyn B Renfree

Abstract

Genomic imprinting causes parent-of-origin specific gene expression by differential epigenetic modifications between two parental genomes. We previously reported that there is no evidence of genomic imprinting of CDKN1C in the KCNQ1 domain in the placenta of an Australian marsupial, the tammar wallaby (Macropus eugenii) whereas tammar IGF2 and H19, located adjacent to the KCNQ1 domain in eutherian mammals, are imprinted. We have now identified and characterised the marsupial orthologue of PHLDA2, another gene in the KCNQ1 domain (also known as IPL or TSSC3) that is imprinted in eutherians. In mice, Phlda2 is a dose-sensitive negative regulator of placental growth, as Cdkn1c is for embryonic growth.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Chile 1 3%
United States 1 3%
Unknown 31 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 24%
Researcher 5 15%
Student > Bachelor 4 12%
Professor 3 9%
Student > Doctoral Student 2 6%
Other 4 12%
Unknown 7 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 36%
Biochemistry, Genetics and Molecular Biology 10 30%
Nursing and Health Professions 1 3%
Veterinary Science and Veterinary Medicine 1 3%
Social Sciences 1 3%
Other 1 3%
Unknown 7 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 August 2011.
All research outputs
#22,758,309
of 25,371,288 outputs
Outputs from BMC Ecology and Evolution
#3,511
of 3,714 outputs
Outputs of similar age
#123,642
of 134,175 outputs
Outputs of similar age from BMC Ecology and Evolution
#49
of 53 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,714 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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