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Lactolisterin BU, a Novel Class II Broad-Spectrum Bacteriocin from Lactococcus lactis subsp. lactis bv. diacetylactis BGBU1-4

Overview of attention for article published in Applied and Environmental Microbiology, November 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

blogs
1 blog
twitter
6 tweeters
reddit
1 Redditor

Citations

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13 Dimensions

Readers on

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44 Mendeley
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Title
Lactolisterin BU, a Novel Class II Broad-Spectrum Bacteriocin from Lactococcus lactis subsp. lactis bv. diacetylactis BGBU1-4
Published in
Applied and Environmental Microbiology, November 2017
DOI 10.1128/aem.01519-17
Pubmed ID
Authors

Jelena Lozo, Nemanja Mirkovic, Paula M. O'Connor, Milka Malesevic, Marija Miljkovic, Natalija Polovic, Branko Jovcic, Paul D. Cotter, Milan Kojic

Abstract

Lactococcus lactis subsp. lactis bv. diacetylactis BGBU1-4 produces a novel bacteriocin, lactolisterin BU, with strong antimicrobial activity against many species of Gram-positive bacteria, including important food spoilage and food-borne pathogens such as Listeria monocytogenes, Staphylococcus aureus, Bacillus sp. and streptococci. Lactolisterin BU was extracted from the cell surface of BGBU1-4 by propan-2-ol and purified to homogeneity by C18 solid phase extraction and reversed phase HPLC. The molecular mass of the purified lactolisterin BU was 5160.94 Da and an internal fragment, AVSWAWQH, as determined by N-terminal sequencing, showed low level similarity with existing antimicrobial peptides. Curing and transformation experiments revealed the presence of a corresponding bacteriocin operon on the smallest plasmid pBU6 (6.2 kb) of strain BGBU1-4. Analysis of the bacteriocin operon revealed a leaderless bacteriocin of 43 amino acids that exhibited similarity to bacteriocin BHT-B (63%), from Streptococcus ratti, a bacteriocin with analogy to aureocin A.IMPORTANCE Lactolisterin BU, broad spectrum leaderless bacteriocin produced by L. lactis subsp. lactis bv. diacetylactis BGBU1-4 strain, expresses strong antimicrobial activity against food spoilage and food-borne pathogens such as Listeria monocytogenes, Staphylococcus aureus, Bacillus sp. and streptococci. Lactolisterin BU showed highest similarity with aureocin like bacteriocins produced by different bacteria. Operon for synthesis is plasmid located on the smallest plasmid pBU6 (6.2 kb) of strain BGBU1-4, indicating possible horizontal transfer among producers.

Twitter Demographics

The data shown below were collected from the profiles of 6 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 44 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 25%
Student > Master 4 9%
Other 3 7%
Student > Doctoral Student 3 7%
Professor > Associate Professor 3 7%
Other 7 16%
Unknown 13 30%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 25%
Biochemistry, Genetics and Molecular Biology 9 20%
Immunology and Microbiology 4 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Veterinary Science and Veterinary Medicine 1 2%
Other 2 5%
Unknown 15 34%

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 December 2017.
All research outputs
#1,766,243
of 14,365,203 outputs
Outputs from Applied and Environmental Microbiology
#1,174
of 10,556 outputs
Outputs of similar age
#49,243
of 269,200 outputs
Outputs of similar age from Applied and Environmental Microbiology
#30
of 125 outputs
Altmetric has tracked 14,365,203 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 10,556 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 269,200 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 125 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.