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Spirometry reference values in the Brazilian population

Overview of attention for article published in Brazilian Journal of Medical and Biological Research, January 2017
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Spirometry reference values in the Brazilian population
Published in
Brazilian Journal of Medical and Biological Research, January 2017
DOI 10.1590/1414-431x20175700
Pubmed ID

R. Rufino, C.H. Costa, A.J. Lopes, A.I. Maiworm, K. Maynard, L.M.R.A. Silva, R.M. Dias


The aim of the present study was to provide new spirometry reference equations in a sample of the Brazilian population for the following parameters: forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), FEV1/FVC ratio, peak of expiratory flow (PEF), forced expiratory flow at 50% (FEF50%), 75% average vital capacity (FEF25-75%), and average forced expiratory flow time (FEFT). This was a prospective study using results from chest radiographs, electrocardiograms, and questionnaires to investigate the participants' respiratory symptoms, sedentarism, and comorbidities (Charlson comorbidity index). From December 2010 to July 2014, individuals were randomly selected from various locations in the state of Rio de Janeiro. All individuals were examined by a single technician in the morning at the laboratory, and performed the spirometry with the same spirometer. Spirometry values were tabulated for the creation of three equation models: linear regression, logarithmic regression, and logarithms through a method that incorporates the lambda, median, and coefficient of variation (LMS method). Initially, 7003 individuals from both genders were contacted, and 454 were recruited. The data from the new equations were compared with one Brazilian and eight international equations, resulting in a high correlation (r>0.9). The values derived from the LMS method and linear regression were very similar (P>0.5), and both could be used to acquire the reference values for Brazilian spirometry. Data derived from the equations of this study were different from the current Brazilian equation, which could be justified by the different method used.

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 46 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 24%
Researcher 4 9%
Student > Doctoral Student 3 7%
Student > Bachelor 3 7%
Student > Postgraduate 2 4%
Other 5 11%
Unknown 18 39%
Readers by discipline Count As %
Medicine and Dentistry 8 17%
Nursing and Health Professions 6 13%
Agricultural and Biological Sciences 3 7%
Sports and Recreations 2 4%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 7 15%
Unknown 19 41%