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Personalised Medicine

Overview of attention for book
Attention for Chapter 5: The Role of Nitric Oxide from Neurological Disease to Cancer
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31 Mendeley
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Chapter title
The Role of Nitric Oxide from Neurological Disease to Cancer
Chapter number 5
Book title
Personalised Medicine
Published in
Advances in experimental medicine and biology, January 2017
DOI 10.1007/978-3-319-60733-7_5
Pubmed ID
Book ISBNs
978-3-31-960731-3, 978-3-31-960733-7

Ahmed Maher, Mohamed F. Abdel Rahman, Mohamed Z. Gad


Until the beginning of the 1980s, nitric oxide (NO) was just a toxic molecule of a lengthy list of environmental pollutants such as cigarette smoke and smog. In fact, NO had a very bad reputation of being destroyer of ozone, suspected carcinogen and precursor of acid rain. However, by the early 1990s it was well recognized by the medical research community. Over the last two decades, the picture has been totally changed. Diverse lines of evidence have converged to show that this sometime poison is a fundamental player in the everyday business of the human body. NO activity was probed in the brain, arteries, immune system, liver, pancreas, uterus, peripheral nerves, lungs, and almost every system in the human body. NO is a major player in the cardiovascular system as it is involved in regulating blood pressure. In the CNS, it is involved in memory formation and the regulation of cerebral blood flow to ensure adequate supply of blood to the brain. Because NO is involved in many pathways, it has a role in several diseases related to modern life as hypertension, coronary heart diseases, Alzheimer's Disease, stroke and cancer. This chapter focuses on the discussion of the role of NO in neurological diseases and cancer and how can this Janus-faced molecule play a role in the pathology and personalized treatment of these diseases.

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 31 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 26%
Student > Ph. D. Student 4 13%
Researcher 4 13%
Student > Bachelor 3 10%
Student > Doctoral Student 2 6%
Other 2 6%
Unknown 8 26%
Readers by discipline Count As %
Medicine and Dentistry 10 32%
Nursing and Health Professions 4 13%
Biochemistry, Genetics and Molecular Biology 3 10%
Agricultural and Biological Sciences 2 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Other 3 10%
Unknown 8 26%