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Mendeley readers
Attention Score in Context
| Title |
Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor
|
|---|---|
| Published in |
Proceedings of the National Academy of Sciences of the United States of America, June 2011
|
| DOI | 10.1073/pnas.1105380108 |
| Pubmed ID | |
| Authors |
Mary O'Connell Motherway, Aldert Zomer, Sinead C. Leahy, Justus Reunanen, Francesca Bottacini, Marcus J. Claesson, Frances O'Brien, Kiera Flynn, Patrick G. Casey, Jose Antonio Moreno Munoz, Breda Kearney, Aileen M. Houston, Caitlin O'Mahony, Des G. Higgins, Fergus Shanahan, Airi Palva, Willem M. de Vos, Gerald F. Fitzgerald, Marco Ventura, Paul W. O'Toole, Douwe van Sinderen |
| Abstract |
Development of the human gut microbiota commences at birth, with bifidobacteria being among the first colonizers of the sterile newborn gastrointestinal tract. To date, the genetic basis of Bifidobacterium colonization and persistence remains poorly understood. Transcriptome analysis of the Bifidobacterium breve UCC2003 2.42-Mb genome in a murine colonization model revealed differential expression of a type IVb tight adherence (Tad) pilus-encoding gene cluster designated "tad(2003)." Mutational analysis demonstrated that the tad(2003) gene cluster is essential for efficient in vivo murine gut colonization, and immunogold transmission electron microscopy confirmed the presence of Tad pili at the poles of B. breve UCC2003 cells. Conservation of the Tad pilus-encoding locus among other B. breve strains and among sequenced Bifidobacterium genomes supports the notion of a ubiquitous pili-mediated host colonization and persistence mechanism for bifidobacteria. |
Mendeley readers
The data shown below were compiled from readership statistics for 229 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | <1% |
| United States | 1 | <1% |
| France | 1 | <1% |
| Unknown | 225 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 62 | 27% |
| Student > Ph. D. Student | 40 | 17% |
| Student > Master | 33 | 14% |
| Student > Bachelor | 25 | 11% |
| Student > Doctoral Student | 15 | 7% |
| Other | 34 | 15% |
| Unknown | 20 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 101 | 44% |
| Biochemistry, Genetics and Molecular Biology | 42 | 18% |
| Immunology and Microbiology | 23 | 10% |
| Medicine and Dentistry | 11 | 5% |
| Chemistry | 6 | 3% |
| Other | 16 | 7% |
| Unknown | 30 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2023.
All research outputs
#4,282,702
of 23,269,984 outputs
Outputs from Proceedings of the National Academy of Sciences of the United States of America
#42,279
of 99,098 outputs
Outputs of similar age
#22,009
of 115,913 outputs
Outputs of similar age from Proceedings of the National Academy of Sciences of the United States of America
#357
of 792 outputs
Altmetric has tracked 23,269,984 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 99,098 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 37.3. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 115,913 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 792 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.