FIRST BRAZILIAN CONSENSUS ON MULTIMODAL TREATMENT OF COLORECTAL LIVER METASTASES. MODULE 1: PRE-TREATMENT EVALUATION

Felipe José Fernandez Coimbra, Heber Salvador de Castro Ribeiro, Márcio Carmona Marques, Paulo Herman, Rubens Chojniak, Antonio Nocchi Kalil, Evanius Garcia Wiermann, Sandro Roberto de Araújo Cavallero, Fabricio Ferreira Coelho, Paulo Henrique de Souza Fernandes, Anderson Arantes Silvestrini, Maria Fernanda Arruda Almeida, Antônio Luis Eiras de Araújo, Marcos Pitombo, Heberton Medeiros Teixeira, Fábio Luiz Waechter, Fábio Gonçalves Ferreira, Alessandro Landskron Diniz, Giuseppe D'Ippolito, Giuseppe D'Ippolito, Maria Dirlei F de Sousa Begnami, Gabriel Prolla, Silvio Márcio Pegoraro Balzan, Thiago Bueno de Oliveira, Luís Arnaldo Szultan, Javier Lendoire, Orlando Jorge Martins Torres

Liver metastases of colorectal cancer are frequent and potentially fatal event in the evolution of patients with these tumors. In this module, was contextualized the clinical situations and parameterized epidemiological data and results of the various treatment modalities established. Was realized deep discussion on detecting and staging metastatic colorectal cancer, as well as employment of imaging methods in the evaluation of response to instituted systemic therapy. The next step was based on the definition of which patients would have their metastases considered resectable and how to expand the amount of patients elegible for modalities with curative intent. Were presented clinical, pathological and molecular prognostic factors, validated to be taken into account in clinical practice.