Title |
Collagen induced arthritis increases secondary metastasis in MMTV-PyV MT mouse model of mammary cancer
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Published in |
BMC Cancer, August 2011
|
DOI | 10.1186/1471-2407-11-365 |
Pubmed ID | |
Authors |
Lopamudra Das Roy, Sriparna Ghosh, Latha B Pathangey, Teresa L Tinder, Helen E Gruber, Pinku Mukherjee |
Abstract |
Several studies have demonstrated that sites of chronic inflammation are often associated with the establishment and growth of various malignancies. A common inflammatory condition in humans is autoimmune arthritis (AA). Although AA and cancer are different diseases, many of the underlying processes that contribute to the disorders of the joints and connective tissue that characterize AA also affect cancer progression and metastasis. Systemically, AA can lead to cellular infiltration and inflammation of the lungs. Several studies have reported statistically significant risk ratios between AA and breast cancer. Despite this knowledge being available, there has been minimal research linking breast cancer, arthritis, and metastasis associated with breast cancer. Notably both diseases are extremely prevalent in older post-menopausal women. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 3 | 38% |
United Kingdom | 1 | 13% |
Unknown | 4 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 8 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 2% |
Unknown | 43 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 10 | 23% |
Researcher | 4 | 9% |
Professor | 4 | 9% |
Other | 3 | 7% |
Student > Master | 3 | 7% |
Other | 7 | 16% |
Unknown | 13 | 30% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 9 | 20% |
Medicine and Dentistry | 9 | 20% |
Immunology and Microbiology | 4 | 9% |
Biochemistry, Genetics and Molecular Biology | 2 | 5% |
Mathematics | 1 | 2% |
Other | 3 | 7% |
Unknown | 16 | 36% |