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[VITAMIN B12 DEFICIENCY ASSOCIATED WITH HIGH DOSES OD METFORMIN IN OLDER PEOPLE DIABETIC.]

Overview of attention for article published in Nutricion Hospitalaria, May 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (74th percentile)

Mentioned by

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5 tweeters

Citations

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5 Dimensions

Readers on

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86 Mendeley
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Title
[VITAMIN B12 DEFICIENCY ASSOCIATED WITH HIGH DOSES OD METFORMIN IN OLDER PEOPLE DIABETIC.]
Published in
Nutricion Hospitalaria, May 2014
DOI 10.3305/nh.2014.29.6.7405
Pubmed ID
Authors

Hugo Sánchez, Dominique Masferrer, Lydia Lera, Estrella Arancibia, Barbara Angel, Cecilia Albala, Sánchez, Hugo, Masferrer, Dominique, Lera, Lydia, Arancibia, Estrella, Ángel, Bárbara, Albala, Cecilia

Abstract

Introduction: The aim of the study was to estimate if B12 deficiency is associated with the use of metformin in the elderly diabetics. Methods: Case-control study in diabetic OP. Cases (n = 137) were defined as elderly with B12 < 221 pmol/L and controls (n = 279) elderly with B12 > 221 pmol/L. Four categories of metformin use were defined: non-users, ≤850 mg/day, > 850 and < 2,550 mg/day and ≥2,550 mg/day. Metformin ≥2,550 mg/day was high doses considered. The crude OR for B12 deficiency and consumption of Metformin were calculated. Logistic regression models were developed to explore the association between B12 deficiency and metformin dose. The research protocol was approved by the Ethics Committee of INTA. Results: The age of cases and controls was (70.2 years vs 68.6 years (p < 0.05). The 62% were women in cases vs 74.9% in controls (p < 0.05). The 73% of cases and 76% of controls used metformin (p < 0.05) the average consumption of metformin was de 1,954.3 mg/day (SD: 1,063.2) in cases and 1,696.6 mg/day (SD: 1,074.4) in controls (p < 0.05). The use of 2,550 mg/day was observed in 29.2% of cases and 19.3% for controls (p < 0.05). It was observed that OP who consumed high doses of metformin had 1.9 times the risk of B12 deficiency (OR: 1.9; 95%CI: 1,08- 3,30). Conclusion: These results show a strong association between high doses of metformin and low levels of vitamin B12 in diabetic elderly. This project was funded by FONIS SA11I2092.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 1%
Unknown 85 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 30 35%
Student > Master 9 10%
Student > Postgraduate 7 8%
Other 6 7%
Student > Doctoral Student 5 6%
Other 13 15%
Unknown 16 19%
Readers by discipline Count As %
Medicine and Dentistry 30 35%
Biochemistry, Genetics and Molecular Biology 10 12%
Nursing and Health Professions 9 10%
Agricultural and Biological Sciences 6 7%
Pharmacology, Toxicology and Pharmaceutical Science 4 5%
Other 11 13%
Unknown 16 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 November 2021.
All research outputs
#5,255,160
of 19,561,042 outputs
Outputs from Nutricion Hospitalaria
#61
of 687 outputs
Outputs of similar age
#49,565
of 198,163 outputs
Outputs of similar age from Nutricion Hospitalaria
#1
of 1 outputs
Altmetric has tracked 19,561,042 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 687 research outputs from this source. They receive a mean Attention Score of 2.7. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 198,163 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them