Title |
Epigenetic response in mice mastitis: Role of histone H3 acetylation and microRNA(s) in the regulation of host inflammatory gene expression during Staphylococcus aureus infection
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Published in |
Clinical Epigenetics, June 2014
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DOI | 10.1186/1868-7083-6-12 |
Pubmed ID | |
Authors |
Rahul Modak, Susweta Das Mitra, Madavan Vasudevan, Paramanandhan Krishnamoorthy, Manoj Kumar, Akshay V Bhat, Mani Bhuvana, Sankar K Ghosh, Bibek R Shome, Tapas K Kundu |
Abstract |
There is renewed interest towards understanding the host-pathogen interaction in the light of epigenetic modifications. Although epithelial tissue is the major site for host-pathogen interactions, there is handful of studies to show how epithelial cells respond to pathogens. Bacterial infection in the mammary gland parenchyma induces local and subsequently systemic inflammation that results in a complex disease called mastitis. Globally Staphylococcus aureus is the single largest mastitis pathogen and the infection can ultimately result in either subclinical or chronic and sometimes lifelong infection. |
X Demographics
Geographical breakdown
Country | Count | As % |
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India | 2 | 40% |
Germany | 1 | 20% |
United Kingdom | 1 | 20% |
France | 1 | 20% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 80% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 45 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 10 | 22% |
Student > Ph. D. Student | 9 | 20% |
Student > Master | 7 | 16% |
Student > Bachelor | 3 | 7% |
Professor > Associate Professor | 3 | 7% |
Other | 6 | 13% |
Unknown | 7 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 16 | 36% |
Biochemistry, Genetics and Molecular Biology | 8 | 18% |
Veterinary Science and Veterinary Medicine | 5 | 11% |
Immunology and Microbiology | 3 | 7% |
Engineering | 2 | 4% |
Other | 3 | 7% |
Unknown | 8 | 18% |