Title |
Glucose-6-phosphate dehydrogenase polymorphisms and susceptibility to mild malaria in Dogon and Fulani, Mali
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Published in |
Malaria Journal, July 2014
|
DOI | 10.1186/1475-2875-13-270 |
Pubmed ID | |
Authors |
Bakary Maiga, Amagana Dolo, Susana Campino, Nuno Sepulveda, Patrick Corran, Kirk A Rockett, Marita Troye-Blomberg, Ogobara K Doumbo, Taane G Clark |
Abstract |
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is associated with protection from severe malaria, and potentially uncomplicated malaria phenotypes. It has been documented that G6PD deficiency in sub-Saharan Africa is due to the 202A/376G G6PD A-allele, and association studies have used genotyping as a convenient technique for epidemiological studies. However, recent studies have shown discrepancies in G6PD202/376 associations with severe malaria. There is evidence to suggest that other G6PD deficiency alleles may be common in some regions of West Africa, and that allelic heterogeneity could explain these discrepancies. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 1% |
Portugal | 1 | 1% |
Italy | 1 | 1% |
Zimbabwe | 1 | 1% |
Unknown | 88 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 15 | 16% |
Researcher | 13 | 14% |
Student > Bachelor | 7 | 8% |
Other | 6 | 7% |
Student > Postgraduate | 6 | 7% |
Other | 18 | 20% |
Unknown | 27 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 18 | 20% |
Agricultural and Biological Sciences | 16 | 17% |
Medicine and Dentistry | 15 | 16% |
Social Sciences | 4 | 4% |
Nursing and Health Professions | 2 | 2% |
Other | 9 | 10% |
Unknown | 28 | 30% |