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Genomic Insights into the Origin of Parasitism in the Emerging Plant Pathogen Bursaphelenchus xylophilus

Overview of attention for article published in PLoS Pathogens, September 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (94th percentile)

Mentioned by

blogs
1 blog
twitter
3 tweeters
wikipedia
1 Wikipedia page
f1000
1 research highlight platform

Citations

dimensions_citation
272 Dimensions

Readers on

mendeley
240 Mendeley
citeulike
5 CiteULike
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Title
Genomic Insights into the Origin of Parasitism in the Emerging Plant Pathogen Bursaphelenchus xylophilus
Published in
PLoS Pathogens, September 2011
DOI 10.1371/journal.ppat.1002219
Pubmed ID
Authors

Taisei Kikuchi, James A. Cotton, Jonathan J. Dalzell, Koichi Hasegawa, Natsumi Kanzaki, Paul McVeigh, Takuma Takanashi, Isheng J. Tsai, Samuel A. Assefa, Peter J. A. Cock, Thomas Dan Otto, Martin Hunt, Adam J. Reid, Alejandro Sanchez-Flores, Kazuko Tsuchihara, Toshiro Yokoi, Mattias C. Larsson, Johji Miwa, Aaron G. Maule, Norio Sahashi, John T. Jones, Matthew Berriman

Abstract

Bursaphelenchus xylophilus is the nematode responsible for a devastating epidemic of pine wilt disease in Asia and Europe, and represents a recent, independent origin of plant parasitism in nematodes, ecologically and taxonomically distinct from other nematodes for which genomic data is available. As well as being an important pathogen, the B. xylophilus genome thus provides a unique opportunity to study the evolution and mechanism of plant parasitism. Here, we present a high-quality draft genome sequence from an inbred line of B. xylophilus, and use this to investigate the biological basis of its complex ecology which combines fungal feeding, plant parasitic and insect-associated stages. We focus particularly on putative parasitism genes as well as those linked to other key biological processes and demonstrate that B. xylophilus is well endowed with RNA interference effectors, peptidergic neurotransmitters (including the first description of ins genes in a parasite) stress response and developmental genes and has a contracted set of chemosensory receptors. B. xylophilus has the largest number of digestive proteases known for any nematode and displays expanded families of lysosome pathway genes, ABC transporters and cytochrome P450 pathway genes. This expansion in digestive and detoxification proteins may reflect the unusual diversity in foods it exploits and environments it encounters during its life cycle. In addition, B. xylophilus possesses a unique complement of plant cell wall modifying proteins acquired by horizontal gene transfer, underscoring the impact of this process on the evolution of plant parasitism by nematodes. Together with the lack of proteins homologous to effectors from other plant parasitic nematodes, this confirms the distinctive molecular basis of plant parasitism in the Bursaphelenchus lineage. The genome sequence of B. xylophilus adds to the diversity of genomic data for nematodes, and will be an important resource in understanding the biology of this unusual parasite.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 240 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 3 1%
Canada 2 <1%
United Kingdom 2 <1%
Portugal 2 <1%
Czechia 1 <1%
South Africa 1 <1%
Sweden 1 <1%
Australia 1 <1%
France 1 <1%
Other 5 2%
Unknown 221 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 58 24%
Student > Ph. D. Student 42 18%
Student > Master 28 12%
Student > Bachelor 23 10%
Student > Doctoral Student 16 7%
Other 47 20%
Unknown 26 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 154 64%
Biochemistry, Genetics and Molecular Biology 27 11%
Environmental Science 9 4%
Chemistry 3 1%
Immunology and Microbiology 2 <1%
Other 13 5%
Unknown 32 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 June 2015.
All research outputs
#1,506,799
of 17,826,855 outputs
Outputs from PLoS Pathogens
#1,705
of 7,557 outputs
Outputs of similar age
#8,229
of 104,462 outputs
Outputs of similar age from PLoS Pathogens
#8
of 124 outputs
Altmetric has tracked 17,826,855 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,557 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.0. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 104,462 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 124 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.