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Neurophysiology of Sleep and Wakefulness: Basic Science and Clinical Implications

Overview of attention for article published in Current Neuropharmacology, December 2008
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#24 of 798)
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

news
4 news outlets
blogs
3 blogs
twitter
9 tweeters
facebook
1 Facebook page
wikipedia
5 Wikipedia pages

Citations

dimensions_citation
187 Dimensions

Readers on

mendeley
584 Mendeley
citeulike
1 CiteULike
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Title
Neurophysiology of Sleep and Wakefulness: Basic Science and Clinical Implications
Published in
Current Neuropharmacology, December 2008
DOI 10.2174/157015908787386050
Pubmed ID
Authors

Jonathan Schwartz, Thomas Roth

Abstract

Increased attention to the prevalence of excessive sleepiness has led to a clear need to treat this symptom, thus reinforcing the need for a greater understanding of the neurobiology of sleep and wakefulness. Although the physiological mechanisms of sleep and wakefulness are highly interrelated, recent research reveals that there are distinct differences in the active brain processing and the specific neurochemical systems involved in the two states. In this review, we will examine the specific neuronal pathways, transmitters, and receptors composing the ascending arousal system that flow from the brainstem through the thalamus, hypothalamus, and basal forebrain to the cerebral cortex. We will also discuss the mutually inhibitory interaction between the core neuronal components of this arousal system and the sleep-active neurons in the ventrolateral preoptic nucleus, which serves as a brainstem-switch, regulating the stability of the sleep-wake states. In addition, we will review the role of homeostatic and circadian processes in the sleep-wake cycle, including the influence of the suprachiasmatic nucleus on coordination of sleep-wake systems. Finally, we will summarize how the above processes are reflected in disorders of sleep and wakefulness, including insomnia, narcolepsy, disorders associated with fragmented sleep, circadian rhythm sleep disorders, and primary neurological disorders such as Parkinson's and Alzheimer's diseases.

Twitter Demographics

The data shown below were collected from the profiles of 9 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 584 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 9 2%
France 4 <1%
India 2 <1%
Japan 2 <1%
Denmark 2 <1%
United Kingdom 2 <1%
Italy 1 <1%
Australia 1 <1%
Netherlands 1 <1%
Other 8 1%
Unknown 552 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 94 16%
Student > Ph. D. Student 92 16%
Student > Bachelor 90 15%
Researcher 84 14%
Student > Postgraduate 46 8%
Other 104 18%
Unknown 74 13%
Readers by discipline Count As %
Medicine and Dentistry 140 24%
Agricultural and Biological Sciences 97 17%
Neuroscience 82 14%
Psychology 57 10%
Engineering 26 4%
Other 87 15%
Unknown 95 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 58. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 May 2022.
All research outputs
#552,963
of 21,223,235 outputs
Outputs from Current Neuropharmacology
#24
of 798 outputs
Outputs of similar age
#2,198
of 113,106 outputs
Outputs of similar age from Current Neuropharmacology
#1
of 11 outputs
Altmetric has tracked 21,223,235 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 798 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.3. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 113,106 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.