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Sequence-based detection of mutations in cadherin 1 to determine the prevalence of germline mutations in patients with invasive lobular carcinoma of the breast

Overview of attention for article published in Hereditary Cancer in Clinical Practice, July 2014
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Title
Sequence-based detection of mutations in cadherin 1 to determine the prevalence of germline mutations in patients with invasive lobular carcinoma of the breast
Published in
Hereditary Cancer in Clinical Practice, July 2014
DOI 10.1186/1897-4287-12-17
Pubmed ID
Authors

Allyson L Valente, Seth Rummel, Craig D Shriver, Rachel E Ellsworth

Abstract

Loss of cadherin 1 (CDH1) expression, which is normally involved in cell adhesion and maintenance of tissue architecture, is a hallmark of invasive lobular carcinoma (ILCA). Because hereditary cancers may require different risk reduction, counseling and treatment options than sporadic cancer, it is critical to determine the prevalence of germline CDH1 mutations in patients with ILCA.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 6%
Unknown 15 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 38%
Student > Ph. D. Student 4 25%
Lecturer > Senior Lecturer 1 6%
Other 1 6%
Student > Bachelor 1 6%
Other 2 13%
Unknown 1 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 31%
Medicine and Dentistry 4 25%
Biochemistry, Genetics and Molecular Biology 2 13%
Nursing and Health Professions 1 6%
Psychology 1 6%
Other 1 6%
Unknown 2 13%