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18 F-Fluoride positron emission tomography/computed tomography for noninvasive in vivo quantification of pathophysiological bone metabolism in experimental murine arthritis

Overview of attention for article published in Arthritis Research & Therapy, July 2014
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3 X users

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25 Dimensions

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30 Mendeley
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Title
18 F-Fluoride positron emission tomography/computed tomography for noninvasive in vivo quantification of pathophysiological bone metabolism in experimental murine arthritis
Published in
Arthritis Research & Therapy, July 2014
DOI 10.1186/ar4670
Pubmed ID
Authors

Ingo M Irmler, Peter Gebhardt, Bianca Hoffmann, Thomas Opfermann, Marc-Thilo Figge, Hans P Saluz, Thomas Kamradt

Abstract

Evaluation of disease severity in experimental models of rheumatoid arthritis is inevitably associated with assessment of structural bone damage. A noninvasive imaging technology allowing objective quantification of pathophysiological alterations of bone structure in rodents could substantially extend the methods used to date in preclinical arthritis research for staging of autoimmune disease severity or efficacy of therapeutical intervention. Sodium 18 F-fluoride (18 F-NaF) is a bone-seeking tracer well-suited for molecular imaging. Therefore, we systematically examined the use of 18 F-NaF positron emission tomography/computed tomography (PET/CT) in mice with glucose-6-phosphate isomerase (G6PI)-induced arthritis for quantification of pathological bone metabolism.

X Demographics

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 30 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 23%
Researcher 5 17%
Student > Doctoral Student 3 10%
Other 3 10%
Professor > Associate Professor 2 7%
Other 5 17%
Unknown 5 17%
Readers by discipline Count As %
Medicine and Dentistry 10 33%
Biochemistry, Genetics and Molecular Biology 3 10%
Nursing and Health Professions 3 10%
Engineering 3 10%
Chemistry 2 7%
Other 5 17%
Unknown 4 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 October 2017.
All research outputs
#15,983,785
of 25,374,917 outputs
Outputs from Arthritis Research & Therapy
#2,329
of 3,381 outputs
Outputs of similar age
#127,549
of 239,413 outputs
Outputs of similar age from Arthritis Research & Therapy
#23
of 41 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 36th percentile – i.e., 36% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 239,413 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.