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Mycophenolate mofetil versus methotrexate for prevention of graft-versus-host disease in people receiving allogeneic hematopoietic stem cell transplantation

Overview of attention for article published in Cochrane database of systematic reviews, July 2014
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  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
8 tweeters

Citations

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37 Dimensions

Readers on

mendeley
122 Mendeley

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Title
Mycophenolate mofetil versus methotrexate for prevention of graft-versus-host disease in people receiving allogeneic hematopoietic stem cell transplantation
Published in
Cochrane database of systematic reviews, July 2014
DOI 10.1002/14651858.cd010280.pub2
Pubmed ID
25061777
Authors

Mohamed Kharfan-Dabaja, Rahul Mhaskar, Tea Reljic, Joseph Pidala, Janelle B Perkins, Benjamin Djulbegovic, Ambuj Kumar

Abstract

Allogeneic hematopoietic stem cell transplantation (allo-HCT) is associated with improved outcomes for people with various hematologic diseases; however, the morbidity and mortality resulting from acute and subsequently chronic graft-versus-host disease (GVHD) pose a serious challenge to wider applicability of allo-HCT. Intravenous methotrexate in combination with a calcineurin inhibitor, cyclosporine or tacrolimus, is a widely used regimen for the prophylaxis of acute GVHD, but the administration of methotrexate is associated with a number of adverse events. Mycophenolate mofetil, in combination with a calcineurin inhibitor, has been used extensively in people undergoing allo-HCT. Conflicting results regarding various clinical outcomes following allo-HCT have been observed when comparing mycophenolate mofetil-based regimens against methotrexate-based regimens for acute GVHD prophylaxis.

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Twitter Demographics

The data shown below were collected from the profiles of 8 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 122 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
South Africa 1 <1%
Brazil 1 <1%
Unknown 120 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 22 18%
Researcher 16 13%
Student > Bachelor 15 12%
Student > Postgraduate 13 11%
Student > Ph. D. Student 11 9%
Other 22 18%
Unknown 23 19%
Readers by discipline Count As %
Medicine and Dentistry 54 44%
Nursing and Health Professions 10 8%
Social Sciences 7 6%
Biochemistry, Genetics and Molecular Biology 6 5%
Psychology 5 4%
Other 13 11%
Unknown 27 22%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 January 2015.
All research outputs
#4,123,543
of 15,418,109 outputs
Outputs from Cochrane database of systematic reviews
#6,753
of 11,179 outputs
Outputs of similar age
#47,663
of 194,584 outputs
Outputs of similar age from Cochrane database of systematic reviews
#143
of 219 outputs
Altmetric has tracked 15,418,109 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 11,179 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 23.1. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,584 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 219 others from the same source and published within six weeks on either side of this one. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.

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