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Nonsteroidal anti-inflammatory drugs and their risk: a story still in development

Overview of attention for article published in Arthritis Research & Therapy, January 2013
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1 tweeter

Citations

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47 Mendeley
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Title
Nonsteroidal anti-inflammatory drugs and their risk: a story still in development
Published in
Arthritis Research & Therapy, January 2013
DOI 10.1186/ar4173
Pubmed ID
Authors

Lee S Simon

Abstract

NSAIDs are anti-inflammatory, analgesic, and antipyretic agents, and they are typically used chronically to reduce pain, decrease stiffness, and improve function in patients with osteoarthritis, rheumatoid arthritis, and other forms of arthritis. Additionally, NSAIDs are also used for the more acute treatment of pain including headache, dysmenorrhea, and postoperative pain. However, NSAID use conveys potential significant adverse events that include gastrointestinal ulcers with consequential bleeding, perforation or obstruction, renal dysfunction and consequent renal failure, cardiovascular events, as well as the risk for death. Despite the many available forms of NSAIDs, including injectable as well as topical, oral dosing is the most common route, usually the one route consistently associated with chronic use and thus the one that carries the most risk. In the last several years, several topical NSAIDs including either diclofenac ibuprofen or salicylates for chronic pain have been approved in the United States while similar drugs have been available in Europe for years. One study of a diclofenac topical liquid included an oral diclofenac comparator, and demonstrated no difference in efficacy between the two therapies in treatment for the pain of osteoarthritis in the knee.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 2%
Argentina 1 2%
Unknown 45 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 15%
Student > Bachelor 6 13%
Student > Postgraduate 5 11%
Researcher 5 11%
Other 3 6%
Other 13 28%
Unknown 8 17%
Readers by discipline Count As %
Medicine and Dentistry 18 38%
Agricultural and Biological Sciences 7 15%
Pharmacology, Toxicology and Pharmaceutical Science 3 6%
Nursing and Health Professions 3 6%
Psychology 1 2%
Other 2 4%
Unknown 13 28%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 July 2014.
All research outputs
#5,420,807
of 7,203,133 outputs
Outputs from Arthritis Research & Therapy
#1,056
of 1,335 outputs
Outputs of similar age
#112,269
of 175,232 outputs
Outputs of similar age from Arthritis Research & Therapy
#22
of 32 outputs
Altmetric has tracked 7,203,133 research outputs across all sources so far. This one is in the 13th percentile – i.e., 13% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,335 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 175,232 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.