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Cyclophilin A from Schistosoma japonicum promotes a Th2 response in mice

Overview of attention for article published in Parasites & Vectors, November 2013
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Title
Cyclophilin A from Schistosoma japonicum promotes a Th2 response in mice
Published in
Parasites & Vectors, November 2013
DOI 10.1186/1756-3305-6-330
Pubmed ID
Authors

Jinghui Li, Wenjia Zhuang, Li Cong, Wenjun Shi, Xingyan Cai, Fengjuan Huang, Yiteng Liao, Yiyang Liu, Jun Li, Chunxia Chen, Xiao-Ping Chen

Abstract

Schistosomiasis is a chronic infection, where the host immune response to the parasite changes from a predominantly Th1 to Th2 phenotype, when parasite enters the egg stage, restraining the host inflammatory immune responses to achieve a longer survival in the host. On the other hand, the development of Th2 responses causes immunopathological changes such as liver fibrosis. Therefore identification of schistosome-derived Th2 inducing molecules is important in the understanding of pathogenesis of schistosomiasis. A cyclophilin A homologue of Schistosoma japonicum was reported to be an egg-stage specific antigen, but its immunogenicity and immunoregulatory activities remain unknown.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 20%
Student > Ph. D. Student 3 20%
Other 2 13%
Student > Doctoral Student 2 13%
Student > Master 2 13%
Other 2 13%
Unknown 1 7%
Readers by discipline Count As %
Medicine and Dentistry 5 33%
Agricultural and Biological Sciences 3 20%
Immunology and Microbiology 2 13%
Earth and Planetary Sciences 1 7%
Social Sciences 1 7%
Other 1 7%
Unknown 2 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 August 2014.
All research outputs
#20,233,547
of 22,759,618 outputs
Outputs from Parasites & Vectors
#4,835
of 5,452 outputs
Outputs of similar age
#262,780
of 302,103 outputs
Outputs of similar age from Parasites & Vectors
#194
of 229 outputs
Altmetric has tracked 22,759,618 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,452 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 302,103 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 229 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.