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Mitochondrial haplogroups modify the effect of black carbon on age-related cognitive impairment

Overview of attention for article published in Environmental Health, May 2014
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Title
Mitochondrial haplogroups modify the effect of black carbon on age-related cognitive impairment
Published in
Environmental Health, May 2014
DOI 10.1186/1476-069x-13-42
Pubmed ID
Authors

Elena Colicino, Melinda C Power, David G Cox, Marc G Weisskopf, Lifang Hou, Stacy E Alexeeff, Marco Sanchez-Guerra, Pantel Vokonas, Avron Spiro III, Joel Schwartz, Andrea A Baccarelli

Abstract

Traffic-related air pollution has been linked with impaired cognition in older adults, possibly due to effects of oxidative stress on the brain. Mitochondria are the main source of cellular oxidation. Haplogroups in mitochondrial DNA (mtDNA) mark individual differences in oxidative potential and are possible determinants of neurodegeneration. The aim of this study was to investigate whether mtDNA haplogroups determined differential susceptibility to cognitive effects of long-term exposure to black carbon (BC), a marker of traffic-related air pollution.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 1%
Unknown 69 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 21%
Student > Ph. D. Student 11 16%
Student > Master 9 13%
Student > Bachelor 5 7%
Student > Doctoral Student 4 6%
Other 10 14%
Unknown 16 23%
Readers by discipline Count As %
Medicine and Dentistry 15 21%
Environmental Science 8 11%
Biochemistry, Genetics and Molecular Biology 6 9%
Psychology 5 7%
Social Sciences 5 7%
Other 12 17%
Unknown 19 27%