Report for: Breast-Cancer Risk in Families with Mutations in PALB2

Title	Breast-Cancer Risk in Families with Mutations in PALB2
Published in	New England Journal of Medicine, August 2014
DOI	10.1056/nejmoa1400382
Pubmed ID	25099575
Authors	Antonis C. Antoniou, Silvia Casadei, Tuomas Heikkinen, Daniel Barrowdale, Katri Pylkäs, Jonathan Roberts, Andrew Lee, Deepak Subramanian, Kim De Leeneer, Florentia Fostira, Eva Tomiak, Susan L. Neuhausen, Zhi L. Teo, Sofia Khan, Kristiina Aittomäki, Jukka S. Moilanen, Clare Turnbull, Sheila Seal, Arto Mannermaa, Anne Kallioniemi, Geoffrey J. Lindeman, Saundra S. Buys, Irene L. Andrulis, Paolo Radice, Carlo Tondini, Siranoush Manoukian, Amanda E. Toland, Penelope Miron, Jeffrey N. Weitzel, Susan M. Domchek, Bruce Poppe, Kathleen B.M. Claes, Drakoulis Yannoukakos, Patrick Concannon, Jonine L. Bernstein, Paul A. James, Douglas F. Easton, David E. Goldgar, John L. Hopper, Nazneen Rahman, Paolo Peterlongo, Heli Nevanlinna, Mary-Claire King, Fergus J. Couch, Melissa C. Southey, Robert Winqvist, William D. Foulkes, Marc Tischkowitz
Abstract	Germline loss-of-function mutations in PALB2 are known to confer a predisposition to breast cancer. However, the lifetime risk of breast cancer that is conferred by such mutations remains unknown.

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Twitter Demographics

The data shown below were collected from the profiles of 238 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Geographical breakdown

Country	Count	As %
United States	92	39%
United Kingdom	18	8%
Spain	15	6%
Canada	6	3%
Italy	5	2%
Colombia	3	1%
Australia	3	1%
France	3	1%
Venezuela, Bolivarian Republic of	3	1%
Other	17	7%
Unknown	73	31%

Demographic breakdown

Type	Count	As %
Members of the public	143	60%
Scientists	50	21%
Practitioners (doctors, other healthcare professionals)	39	16%
Science communicators (journalists, bloggers, editors)	6	3%

Mendeley readers

The data shown below were compiled from readership statistics for 433 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country	Count	As %
United States	4	<1%
Canada	3	<1%
Germany	2	<1%
United Kingdom	2	<1%
Chile	1	<1%
France	1	<1%
Argentina	1	<1%
Finland	1	<1%
Unknown	418	97%

Demographic breakdown

Readers by professional status	Count	As %
Student > Master	97	22%
Researcher	69	16%
Student > Ph. D. Student	59	14%
Other	49	11%
Student > Bachelor	41	9%
Other	83	19%
Unknown	35	8%

Readers by discipline	Count	As %
Medicine and Dentistry	150	35%
Agricultural and Biological Sciences	108	25%
Biochemistry, Genetics and Molecular Biology	92	21%
Engineering	5	1%
Nursing and Health Professions	4	<1%
Other	23	5%
Unknown	51	12%

Attention Score in Context

This research output has an Altmetric Attention Score of 830. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 October 2019.

All research outputs

#7,875

of 15,097,586 outputs

Outputs from New England Journal of Medicine

#408

of 26,708 outputs

Outputs of similar age

#87

of 194,803 outputs

Outputs of similar age from New England Journal of Medicine

of 352 outputs

Altmetric has tracked 15,097,586 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.

So far Altmetric has tracked 26,708 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 76.7. This one has done particularly well, scoring higher than 98% of its peers.

Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,803 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.

We're also able to compare this research output to 352 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.

Breast-Cancer Risk in Families with Mutations in PALB2

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Geographical breakdown

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Attention Score in Context