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Intratympanic gentamicin treatment for Ménière’s disease: a randomized, double-blind, placebo-controlled trial on dose efficacy - results of a prematurely ended study

Overview of attention for article published in Trials, August 2014
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Title
Intratympanic gentamicin treatment for Ménière’s disease: a randomized, double-blind, placebo-controlled trial on dose efficacy - results of a prematurely ended study
Published in
Trials, August 2014
DOI 10.1186/1745-6215-15-328
Pubmed ID
Authors

Hendrik G Bremer, Ingrid van Rooy, Bas Pullens, Carla Colijn, Inge Stegeman, Hester J van der Zaag-Loonen, Peter Paul van Benthem, Sjaak F L Klis, Wilko Grolman, Tjasse D Bruintjes

Abstract

Gentamicin is used as a therapeutic agent for Ménière's disease because of its vestibulotoxicity causing chemo-ablation of the vestibular sensory epithelia. Its use has increased in recent years. However, there is still no consensus about the dose regimen of gentamicin in the treatment of Ménière's disease. In this study two different dose regimen treatment protocols are compared in a placebo controlled study design. The primary objective is to quantify the treatment effect on dizziness, the secondary objective is hearing evaluation.

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Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Korea, Republic of 1 2%
Unknown 63 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 16%
Student > Postgraduate 9 14%
Researcher 6 9%
Student > Doctoral Student 6 9%
Student > Bachelor 6 9%
Other 13 20%
Unknown 14 22%
Readers by discipline Count As %
Medicine and Dentistry 34 53%
Nursing and Health Professions 3 5%
Neuroscience 2 3%
Biochemistry, Genetics and Molecular Biology 1 2%
Agricultural and Biological Sciences 1 2%
Other 5 8%
Unknown 18 28%