Title |
Antimicrobial and antibiofilm potential of biosurfactants isolated from lactobacilli against multi-drug-resistant pathogens
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Published in |
BMC Microbiology, August 2014
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DOI | 10.1186/1471-2180-14-197 |
Pubmed ID | |
Authors |
Karthik Sambanthamoorthy, Xiaorong Feng, Ruchi Patel, Sneha Patel, Chrysanthi Paranavitana |
Abstract |
Biosurfactants (BS) are amphiphilic compounds produced by microbes, either on the cell surface or secreted extracellularly. BS exhibit strong antimicrobial and anti-adhesive properties, making them good candidates for applications used to combat infections. In this study, our goal was to assess the in vitro antimicrobial, anti-adhesive and anti-biofilm abilities of BS produced by Lactobacillus jensenii and Lactobacillus rhamnosus against clinical Multidrug Resistant (MDR) strains of Acinetobacter baumannii, Escherichia coli, and Staphylococcus aureus (MRSA). Cell-bound BS from both L. jensenii and L. rhamnosus were extracted and isolated. The surface activities of crude BS samples were evaluated using an oil spreading assay. The antimicrobial, anti-adhesive and anti-biofilm activities of both BS against the above mentioned MDR pathogens were determined. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Venezuela, Bolivarian Republic of | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Kazakhstan | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 247 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 35 | 14% |
Student > Master | 32 | 13% |
Researcher | 31 | 12% |
Student > Bachelor | 28 | 11% |
Student > Doctoral Student | 15 | 6% |
Other | 38 | 15% |
Unknown | 70 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 56 | 22% |
Immunology and Microbiology | 34 | 14% |
Biochemistry, Genetics and Molecular Biology | 32 | 13% |
Engineering | 10 | 4% |
Medicine and Dentistry | 8 | 3% |
Other | 31 | 12% |
Unknown | 78 | 31% |