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The role of carbonic anhydrase VI in bitter taste perception: evidence from the Car6 −/− mouse model

Overview of attention for article published in Journal of Biomedical Science, August 2014
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (51st percentile)
  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

Mentioned by

twitter
3 tweeters

Citations

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28 Dimensions

Readers on

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22 Mendeley
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Title
The role of carbonic anhydrase VI in bitter taste perception: evidence from the Car6 −/− mouse model
Published in
Journal of Biomedical Science, August 2014
DOI 10.1186/s12929-014-0082-2
Pubmed ID
Authors

Maarit Patrikainen, Peiwen Pan, Natalia Kulesskaya, Vootele Voikar, Seppo Parkkila

Abstract

Carbonic anhydrase VI (CA VI) is a secretory isozyme of the α-CA gene family. It is highly expressed in the salivary and mammary glands and secreted into saliva and milk. Although CA VI was first described as a gustatory protein, its exact functional roles have remained enigmatic. Interestingly, polymorphism of the CA6 gene was recently linked to bitter taste perception in humans. In this study, we compared the preference of Car6⁻/⁻ and wild-type mice for different taste modalities in an IntelliCage monitoring environment. Morphologies of taste buds, tongue papillae, and von Ebner's glands were evaluated by light microscopy. Cell proliferation and rate of apoptosis in tongue specimens were examined by Ki67 immunostaining and fluorescent DNA fragmentation staining, respectively.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 4 18%
Student > Bachelor 4 18%
Student > Master 4 18%
Researcher 3 14%
Student > Postgraduate 2 9%
Other 2 9%
Unknown 3 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 32%
Medicine and Dentistry 3 14%
Biochemistry, Genetics and Molecular Biology 3 14%
Neuroscience 2 9%
Immunology and Microbiology 1 5%
Other 3 14%
Unknown 3 14%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 August 2014.
All research outputs
#2,122,318
of 4,507,778 outputs
Outputs from Journal of Biomedical Science
#114
of 252 outputs
Outputs of similar age
#50,184
of 113,500 outputs
Outputs of similar age from Journal of Biomedical Science
#6
of 19 outputs
Altmetric has tracked 4,507,778 research outputs across all sources so far. This one is in the 49th percentile – i.e., 49% of other outputs scored the same or lower than it.
So far Altmetric has tracked 252 research outputs from this source. They receive a mean Attention Score of 3.1. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 113,500 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.