Title |
A prospective study of grey matter and cognitive function alterations in chemotherapy-treated breast cancer patients
|
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Published in |
SpringerPlus, August 2014
|
DOI | 10.1186/2193-1801-3-444 |
Pubmed ID | |
Authors |
Chris Lepage, Andra M Smith, Jeremy Moreau, Emily Barlow-Krelina, Nancy Wallis, Barbara Collins, Joyce MacKenzie, Carole Scherling |
Abstract |
Subsequent to chemotherapy treatment, breast cancer patients often report a decline in cognitive functioning that can adversely impact many aspects of their lives. Evidence has mounted in recent years indicating that a portion of breast cancer survivors who have undergone chemotherapy display reduced performance on objective measures of cognitive functioning relative to comparison groups. Neurophysiological support for chemotherapy-related cognitive impairment has been accumulating due to an increase in neuroimaging studies in this field; however, longitudinal studies are limited and have not examined the relationship between structural grey matter alterations and neuropsychological performance. The aim of this study was to extend the cancer-cognition literature by investigating the association between grey matter attenuation and objectively measured cognitive functioning in chemotherapy-treated breast cancer patients. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Australia | 1 | 50% |
United Kingdom | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 1% |
Germany | 1 | 1% |
Unknown | 79 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 15 | 19% |
Researcher | 9 | 11% |
Student > Master | 9 | 11% |
Student > Bachelor | 8 | 10% |
Student > Doctoral Student | 6 | 7% |
Other | 14 | 17% |
Unknown | 20 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 22 | 27% |
Neuroscience | 15 | 19% |
Medicine and Dentistry | 7 | 9% |
Biochemistry, Genetics and Molecular Biology | 4 | 5% |
Agricultural and Biological Sciences | 3 | 4% |
Other | 8 | 10% |
Unknown | 22 | 27% |