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Comparison of metaraminol, phenylephrine and ephedrine in prophylaxis and treatment of hypotension in cesarean section under spinal anesthesia

Overview of attention for article published in Brazilian Journal of Anesthesiology (English edition), September 2014
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About this Attention Score

  • Among the highest-scoring outputs from this source (#16 of 151)
  • Above-average Attention Score compared to outputs of the same age (55th percentile)

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2 tweeters

Citations

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6 Dimensions

Readers on

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27 Mendeley
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Title
Comparison of metaraminol, phenylephrine and ephedrine in prophylaxis and treatment of hypotension in cesarean section under spinal anesthesia
Published in
Brazilian Journal of Anesthesiology (English edition), September 2014
DOI 10.1016/j.bjane.2013.07.014
Pubmed ID
Authors

Fábio Farias de Aragão, Pedro Wanderley de Aragão, Carlos Alberto de Souza Martins, Natalino Salgado Filho, Elizabeth de Souza Barcelos Barroqueiro

Abstract

Maternal hypotension is a common complication after spinal anesthesia for cesarean section, with deleterious effects on the fetus and mother. Among the strategies aimed at minimizing the effects of hypotension, vasopressor administration is the most efficient. The aim of this study was to compare the efficacy of phenylephrine, metaraminol, and ephedrine in the prevention and treatment of hypotension after spinal anesthesia for cesarean section. Ninety pregnant women, not in labor, undergoing cesarean section were randomized into three groups to receive a bolus followed by continuous infusion of vasopressor as follows: phenylephrine group (50μg+50μg/min); metaraminol group (0.25mg+0.25mg/min); ephedrine group (4mg+4mg/min). Infusion dose was doubled when systolic blood pressure decreased to 80% of baseline and a bolus was given when systolic blood pressure decreased below 80%. The infusion dose was divided in half when systolic blood pressure increased to 120% and was stopped when it became higher. The incidence of hypotension, nausea and vomiting, reactive hypertension, bradycardia, tachycardia, Apgar scores, and arterial cord blood gases were assessed at the 1st and 5th minutes. There was no difference in the incidence of hypotension, bradycardia, reactive hypertension, infusion discontinuation, atropine administration or Apgar scores. Rescue boluses were higher only in the ephedrine group compared to metaraminol group. The incidence of nausea and vomiting and fetal acidosis were greater in the ephedrine group. The three drugs were effective in preventing hypotension; however, fetal effects were more frequent in the ephedrine group, although transient.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 26%
Student > Master 6 22%
Other 3 11%
Student > Postgraduate 3 11%
Student > Ph. D. Student 2 7%
Other 2 7%
Unknown 4 15%
Readers by discipline Count As %
Medicine and Dentistry 16 59%
Agricultural and Biological Sciences 2 7%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Linguistics 1 4%
Nursing and Health Professions 1 4%
Other 2 7%
Unknown 4 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 September 2014.
All research outputs
#4,307,719
of 8,617,105 outputs
Outputs from Brazilian Journal of Anesthesiology (English edition)
#16
of 151 outputs
Outputs of similar age
#82,985
of 189,829 outputs
Outputs of similar age from Brazilian Journal of Anesthesiology (English edition)
#1
of 1 outputs
Altmetric has tracked 8,617,105 research outputs across all sources so far. This one is in the 49th percentile – i.e., 49% of other outputs scored the same or lower than it.
So far Altmetric has tracked 151 research outputs from this source. They receive a mean Attention Score of 0.7. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 189,829 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them