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@emily_fri @PulmCrit I don't think there is much difference. Absorption and conversion to prednisolone is quite rapid. Anyway, the effect is small. https://t.co/O8O0VH19a5 Btw, why not inhaled? https://t.co/p6azDOpRQi
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@mmmmmjarvis @muir_hannah There is an increase in adverse drug effects with corticosteroid treatment, which is greater with parenteral administration compared with oral treatment. 2/2 https://t.co/aLEc37M0a7
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@DrToddLee @FranciscoMarty_ What do u mean lower importance? Bc mortality? I would say the strength of evidence is stronger although am no expert https://t.co/3oyuLZgCAe I suspect ur right abt another trial, although I think it would be reasonable to do
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@mmc_im All good studies pointing out that there is no additional benefit of oral vs IV steroids. Here is a cochrane showcasing the highest level of evidence! BTW, this question was the one the residents posed for our next journal club! So we got a heads