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An engineered pathway for the biosynthesis of renewable propane

Overview of attention for article published in Nature Communications, September 2014
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  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

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Title
An engineered pathway for the biosynthesis of renewable propane
Published in
Nature Communications, September 2014
DOI 10.1038/ncomms5731
Pubmed ID
Authors

Pauli Kallio, András Pásztor, Kati Thiel, M. Kalim Akhtar, Patrik R. Jones

Abstract

The deployment of next-generation renewable biofuels can be enhanced by improving their compatibility with the current infrastructure for transportation, storage and utilization. Propane, the bulk component of liquid petroleum gas, is an appealing target as it already has a global market. In addition, it is a gas under standard conditions, but can easily be liquefied. This allows the fuel to immediately separate from the biocatalytic process after synthesis, yet does not preclude energy-dense storage as a liquid. Here we report, for the first time, a synthetic metabolic pathway for producing renewable propane. The pathway is based on a thioesterase specific for butyryl-acyl carrier protein (ACP), which allows native fatty acid biosynthesis of the Escherichia coli host to be redirected towards a synthetic alkane pathway. Propane biosynthesis is markedly stimulated by the introduction of an electron-donating module, optimizing the balance of O2 supply and removal of native aldehyde reductases.

X Demographics

X Demographics

The data shown below were collected from the profiles of 104 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 361 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 9 2%
United Kingdom 6 2%
Germany 2 <1%
Sweden 1 <1%
Iran, Islamic Republic of 1 <1%
Canada 1 <1%
China 1 <1%
Denmark 1 <1%
Unknown 339 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 88 24%
Researcher 81 22%
Student > Master 43 12%
Student > Bachelor 34 9%
Student > Doctoral Student 25 7%
Other 55 15%
Unknown 35 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 127 35%
Biochemistry, Genetics and Molecular Biology 71 20%
Engineering 36 10%
Chemistry 29 8%
Chemical Engineering 9 2%
Other 34 9%
Unknown 55 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 438. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 January 2023.
All research outputs
#63,252
of 25,138,857 outputs
Outputs from Nature Communications
#975
of 55,488 outputs
Outputs of similar age
#474
of 243,780 outputs
Outputs of similar age from Nature Communications
#4
of 654 outputs
Altmetric has tracked 25,138,857 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 55,488 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 55.9. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 243,780 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 654 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.