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Switchable Amplification of Vibrational Circular Dichroism as a Probe of Local Chiral Structure

Overview of attention for article published in Angewandte Chemie. International Edition, September 2014
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Title
Switchable Amplification of Vibrational Circular Dichroism as a Probe of Local Chiral Structure
Published in
Angewandte Chemie. International Edition, September 2014
DOI 10.1002/anie.201407376
Pubmed ID
Authors

Sérgio R. Domingos, Hans J. Sanders, František Hartl, Wybren J. Buma, Sander Woutersen

Abstract

A new method to detect the vibrational circular dichroism (VCD) of a localized part of a chiral molecular system is reported. A local VCD amplifier was implemented, and the distance dependence of the amplification was investigated in a series of peptides. The results indicate a characteristic distance of 2.0±0.3 bonds, which suggests that the amplification is a localized phenomenon. The amplifier can be covalently coupled to a specific part of a molecule, and can be switched ON and OFF electrochemically. By subtracting the VCD spectra obtained when the amplifier is in the ON and OFF states, the VCD of the local environment of the amplifier can be separated from the total VCD spectrum. Switchable local VCD amplification thus makes it possible to "zoom in" on a specific part of a chiral molecule.

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 3%
Unknown 34 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 26%
Student > Master 6 17%
Professor 5 14%
Student > Ph. D. Student 3 9%
Student > Postgraduate 3 9%
Other 4 11%
Unknown 5 14%
Readers by discipline Count As %
Chemistry 23 66%
Physics and Astronomy 2 6%
Agricultural and Biological Sciences 1 3%
Biochemistry, Genetics and Molecular Biology 1 3%
Engineering 1 3%
Other 0 0%
Unknown 7 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 October 2014.
All research outputs
#16,721,208
of 25,373,627 outputs
Outputs from Angewandte Chemie. International Edition
#37,086
of 49,982 outputs
Outputs of similar age
#142,771
of 250,305 outputs
Outputs of similar age from Angewandte Chemie. International Edition
#437
of 708 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 49,982 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 250,305 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 708 others from the same source and published within six weeks on either side of this one. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.