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Tryptophan depletion in chronic fatigue syndrome, a pilot cross-over study

Overview of attention for article published in BMC Research Notes, September 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)

Mentioned by

twitter
9 tweeters
facebook
6 Facebook pages

Citations

dimensions_citation
5 Dimensions

Readers on

mendeley
41 Mendeley
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Title
Tryptophan depletion in chronic fatigue syndrome, a pilot cross-over study
Published in
BMC Research Notes, September 2014
DOI 10.1186/1756-0500-7-650
Pubmed ID
Authors

Gerard KH The, Robbert J Verkes, Durk Fekkes, Gijs Bleijenberg, Jos WM van der Meer, Jan K Buitelaar

Abstract

Chronic fatigue syndrome (CFS) is still an enigmatic disorder. CFS can be regarded as a complex disorder with tremendous impact on lives of CFS-patients. Full recovery without treatment is rare. A somatic explanation for the fatigue is lacking. There is clinical and experimental evidence implicating enhanced serotonergic neurotransmission in CFS. Genetic studies and imaging studies support the hypothesis of upregulated serotonin system in CFS. In line with the hypothesis of an increased serotonergic state in CFS, we performed a randomised clinical trial investigated the effect of 5-HT3 receptor antagonism in CFS. No benefit was found of the 5-HT3 receptor antagonist ondansetron compared to placebo.To further investigate the involvement of serotonin in CFS we performed a placebo controlled cross over pilot study investigating the effect of Acute Tryptophan Depletion.

Twitter Demographics

The data shown below were collected from the profiles of 9 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 41 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 22%
Researcher 7 17%
Student > Master 6 15%
Student > Bachelor 6 15%
Student > Doctoral Student 4 10%
Other 9 22%
Readers by discipline Count As %
Psychology 10 24%
Medicine and Dentistry 8 20%
Agricultural and Biological Sciences 5 12%
Unspecified 4 10%
Nursing and Health Professions 3 7%
Other 11 27%

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 June 2015.
All research outputs
#2,385,547
of 13,559,870 outputs
Outputs from BMC Research Notes
#417
of 3,079 outputs
Outputs of similar age
#30,555
of 170,090 outputs
Outputs of similar age from BMC Research Notes
#1
of 1 outputs
Altmetric has tracked 13,559,870 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,079 research outputs from this source. They receive a mean Attention Score of 4.4. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 170,090 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them