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A novel early precursor cell population from rat bone marrow promotes angiogenesis in vitro

Overview of attention for article published in BMC Molecular and Cell Biology, March 2014
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Title
A novel early precursor cell population from rat bone marrow promotes angiogenesis in vitro
Published in
BMC Molecular and Cell Biology, March 2014
DOI 10.1186/1471-2121-15-12
Pubmed ID
Authors

Andreas Brandl, Quan Yuan, Anja M Boos, Justus P Beier, Andreas Arkudas, Ulrich Kneser, Raymund E Horch, Oliver Bleiziffer

Abstract

Some studies demonstrated therapeutic angiogenesis attributable to the effects of endothelial progenitor cells (EPC), others have reported disappointing results. This may be due to the fact that EPC populations used in these contradictory studies were selected and defined by highly variable and differing experimental protocols. Indeed, the isolation and reliable characterization of ex vivo differentiated EPC raises considerable problems due to the fact there is no biomarker currently available to specifically identify EPC exclusively. On the other hand traditional differentiation of primary immature bone marrow cells towards the endothelial lineage is a time-consuming process of up to 5 weeks. To circumvent these shortcomings, we herein describe a facile method to isolate and enrich a primary cell population from rat bone marrow, combining differential attachment methodology with cell sorting technology.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 20%
Student > Doctoral Student 2 13%
Other 2 13%
Professor > Associate Professor 2 13%
Student > Master 2 13%
Other 4 27%
Readers by discipline Count As %
Medicine and Dentistry 4 27%
Agricultural and Biological Sciences 4 27%
Biochemistry, Genetics and Molecular Biology 2 13%
Arts and Humanities 1 7%
Veterinary Science and Veterinary Medicine 1 7%
Other 2 13%
Unknown 1 7%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 September 2014.
All research outputs
#20,657,128
of 25,374,917 outputs
Outputs from BMC Molecular and Cell Biology
#935
of 1,233 outputs
Outputs of similar age
#175,226
of 238,075 outputs
Outputs of similar age from BMC Molecular and Cell Biology
#11
of 14 outputs
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